A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.4.1.52

Accepted Name
Poly(glycerol-phosphate) alpha-glucosyltransferase.
Alternative Name(s)
UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase.
Reaction catalysed
n UDP-alpha-D-glucose + 4-O-(poly((2R)-glycerophospho)-(2R)-glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-(poly((2R)-2-alpha-D-glucosyl-1-glycerophospho)-(2R)-glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Comment(s)
  • Involved in the biosynthesis of poly glycerol phosphate teichoic acids in bacterial cell walls.
  • This enzyme, isolated from Bacillus subtilis 168, adds an alpha-D- glucose to the free OH groups of the glycerol units.
  • The enzyme has a strong preference for UDP-alpha-glucose as the sugar donor.
  • It has no activity with poly(ribitol phosphate).
Cross-references
BRENDA2.4.1.52
EC2PDB2.4.1.52
ExplorEnz2.4.1.52
PRIAM enzyme-specific profiles2.4.1.52
KEGG Ligand Database for Enzyme Nomenclature2.4.1.52
IUBMB Enzyme Nomenclature2.4.1.52
IntEnz2.4.1.52
MEDLINEFind literature relating to 2.4.1.52
MetaCyc2.4.1.52
UniProtKB/Swiss-Prot
P13484, TAGE_BACSU

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-