ENZYME

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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.4.1.70

Accepted Name
Poly(ribitol-phosphate) alpha-N-acetylglucosaminyltransferase.
Alternative Name(s)
Poly(ribitol-phosphate) N-acetylglucosaminyltransferase.
UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase.
Reaction catalysed
n UDP-N-acetyl-alpha-D-glucosamine + 4-O-(D-ribitylphospho)(n)-di((2R)-1-glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n UDP + 4-O-(2-N-acetyl-alpha-D-glucosaminyl-D-ribitylphospho)(n)-di((2R)-1-glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Comment(s)
Involved in the biosynthesis of poly(ribitol phosphate) teichoic acids in the cell wall of the bacterium Staphylococcus aureus. This enzyme adds an N-acetyl-alpha-D-glucosamine to the hydroxyl group at the 2 position of the ribitol phosphate units. Cf. EC 2.4.1.355.
Cross-references
BRENDA	2.4.1.70
EC2PDB	2.4.1.70
ExplorEnz	2.4.1.70
PRIAM enzyme-specific profiles	2.4.1.70
KEGG Ligand Database for Enzyme Nomenclature	2.4.1.70
IUBMB Enzyme Nomenclature	2.4.1.70
IntEnz	2.4.1.70
MEDLINE	Find literature relating to 2.4.1.70
MetaCyc	2.4.1.70