ID   2.4.1.79
DE   Globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase.
AN   Beta-3GalNAc-T1.
AN   Galactosylgalactosylglucosylceramide beta-D-
AN   acetylgalactosaminyltransferase.
AN   Globoside synthase.
AN   Globoside synthetase.
AN   Uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide
AN   acetylgalactosaminyltransferase.
CA   UDP-N-acetyl-alpha-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-
CA   galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-beta-
CA   D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-
CA   (1->4)-beta-D-glucosyl-(1<->1)-ceramide.
CF   Mn(2+).
CC   -!- Globoside is a neutral glycosphingolipid in human erythrocytes and
CC       has blood-group-P-antigen activity.
CC   -!- UDP-GalNAc is the only sugar donor that is used efficiently by the
CC       enzyme: UDP-Gal and UDP-GlcNAc result in very low enzyme activity.
CC   -!- Lactosylceramide, globoside and gangliosides GM3 and GD3 are not
CC       substrates.
DR   O75752, B3GL1_HUMAN;  Q920V1, B3GL1_MOUSE;  Q793U7, B3GL1_MUSSI;
DR   Q864U6, B3GL1_PIG  ;  Q5RAL7, B3GL1_PONAB;  Q6AY39, B3GL1_RAT  ;
//