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ENZYME

ENZYME entry: EC 2.4.2.57

PURL: https://purl.expasy.org/enzyme/EC/2.4.2.57
Accepted Name
AMP phosphorylase
Alternative Name(s)
AMPpase
nucleoside monophosphate phosphorylase
Reaction catalysed
  • AMP + phosphate = alpha-D-ribose 1,5-bisphosphate + adenine
  • CMP + phosphate = cytosine + alpha-D-ribose 1,5-bisphosphate
  • UMP + phosphate = alpha-D-ribose 1,5-bisphosphate + uracil
Comment(s)
  • The enzyme from archaea is involved in AMP metabolism and CO2 fixation through type III RubisCO enzymes.
  • The activity with CMP and UMP requires activation by cAMP.
Cross-references
BRENDA2.4.2.57
EC2PDB2.4.2.57
ExplorEnz2.4.2.57
KEGG Ligand Database for Enzyme Nomenclature2.4.2.57
IUBMB Enzyme Nomenclature2.4.2.57
MEDLINEFind literature relating to 2.4.2.57
MetaCyc2.4.2.57
Rhea expert-curated reactions2.4.2.57
UniProtKB/Swiss-Prot
O28928, AMPP1_ARCFUO28927, AMPP2_ARCFUA2BJU0, AMPPA_HYPBU
A6UUN0, AMPPA_META3Q8TL01, AMPPA_METACQ0W5A8, AMPPA_METAR
A7I5N0, AMPPA_METB6Q466X0, AMPPA_METBFQ12Z64, AMPPA_METBU
Q2FTS5, AMPPA_METHJQ58081, AMPPA_METJAA2SPI9, AMPPA_METLZ
A4FZL0, AMPPA_METM5A9A6M7, AMPPA_METM6A6VIW6, AMPPA_METM7
Q8Q0P9, AMPPA_METMAA3CSY4, AMPPA_METMJQ6M0E4, AMPPA_METMP
A0B6C9, AMPPA_METTPA6URW3, AMPPA_METVSQ3IP82, AMPPA_NATPD
Q9V163, AMPPA_PYRABQ8U0I2, AMPPA_PYRFUO59251, AMPPA_PYRHO
C5A1L9, AMPPA_THEGJQ5JCX3, AMPPA_THEKOB6YWT7, AMPPA_THEON
A1RWC3, AMPPA_THEPDC6A2A0, AMPPA_THESM

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