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ENZYME entry: EC 2.4.2.61

Accepted Name
Alpha-dystroglycan beta-1,4-xylosyltransferase.
Reaction catalysed
UDP-alpha-D-xylose + 3-O-(Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man)-Ser/Thr-[protein] <=> UDP + 3-O-(beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man)-Ser/Thr-[protein]
Comment(s)
  • This eukaryotic enzyme catalyzes a step in the biosynthesis of the glycan moiety of the membrane protein alpha-dystroglycan.
  • It is specific for the second ribitol 5-phosphate in the nascent glycan chain as acceptor.
Cross-references
BRENDA2.4.2.61
EC2PDB2.4.2.61
ExplorEnz2.4.2.61
PRIAM enzyme-specific profiles2.4.2.61
KEGG Ligand Database for Enzyme Nomenclature2.4.2.61
IUBMB Enzyme Nomenclature2.4.2.61
IntEnz2.4.2.61
MEDLINEFind literature relating to 2.4.2.61
MetaCyc2.4.2.61

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