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ENZYME

ENZYME entry: EC 2.4.2.8

Accepted Name
hypoxanthine phosphoribosyltransferase
Alternative Name(s)
guanine phosphoribosyltransferase
HGPRTase
hypoxanthine-guanine phosphoribosyltransferase
IMP diphosphorylase
IMP pyrophosphorylase
transphosphoribosidase
Reaction catalysed
diphosphate + IMP <=> 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine
Comment(s)
Guanine and purine-6-thiol can replace hypoxanthine.
Cross-references
BRENDA2.4.2.8
EC2PDB2.4.2.8
ExplorEnz2.4.2.8
PRIAM enzyme-specific profiles2.4.2.8
KEGG Ligand Database for Enzyme Nomenclature2.4.2.8
IUBMB Enzyme Nomenclature2.4.2.8
IntEnz2.4.2.8
MEDLINEFind literature relating to 2.4.2.8
MetaCyc2.4.2.8
Rhea expert-curated reactions2.4.2.8
UniProtKB/Swiss-Prot
O66821, HGPRT_AQUAEP37472, HGPRT_BACSUQ839B2, HGPRT_ENTFA
Q02522, HGPRT_LACLAP96794, HGPRT_MYCAVP0A5T1, HGPRT_MYCBO
P47696, HGPRT_MYCGEO69537, HGPRT_MYCLEP75119, HGPRT_MYCPN
P9WHQ8, HGPRT_MYCTOP9WHQ9, HGPRT_MYCTUP37171, HGPRT_RHOCB
Q5HIG5, HGPRT_STAACP65827, HGPRT_STAAMP99085, HGPRT_STAAN
Q6GJG1, HGPRT_STAARQ6GBX8, HGPRT_STAASP65828, HGPRT_STAAW
Q5HRP4, HGPRT_STAEQQ8CQV4, HGPRT_STAESQ8E7Y1, HGPRT_STRA3
Q8E2H3, HGPRT_STRA5Q8DWM8, HGPRT_STRMUP0DD40, HGPRT_STRP3
Q5XEL6, HGPRT_STRP6Q7CNQ9, HGPRT_STRP8Q97TC4, HGPRT_STRPN
P0DD41, HGPRT_STRPQQ8DRP8, HGPRT_STRR6Q5M216, HGPRT_STRT1
Q5M6K8, HGPRT_STRT2P20035, HGXR_PLAFGP07833, HGXR_PLAFK
Q26997, HGXR_TOXGOP51900, HGXR_TRIFOB5IAJ6, HPRT_ACIB4
Q3SZ18, HPRT_BOVINP57291, HPRT_BUCAIQ8K9U8, HPRT_BUCAP
Q6WIT9, HPRT_CANLFQ9W719, HPRT_CHICKQ27541, HPRT_CRIFA
P00494, HPRT_CRIGRQ54NJ8, HPRT_DICDIP0A9M3, HPRT_ECOL6
P0A9M2, HPRT_ECOLID3S0H7, HPRT_FERPAP45078, HPRT_HAEIN
P00492, HPRT_HUMANP43152, HPRT_LEIDOQ6LDD9, HPRT_MACFA
P47959, HPRT_MERUNA6UX50, HPRT_META3Q8TSS8, HPRT_METAC
Q0W496, HPRT_METARQ46C14, HPRT_METBFQ12W31, HPRT_METBU
D7E9E7, HPRT_METEZC7P7L7, HPRT_METFAE3GW42, HPRT_METFV
Q2FSD3, HPRT_METHJF6BB32, HPRT_METIKD5VT38, HPRT_METIM
Q59049, HPRT_METJAQ8TXQ0, HPRT_METKAF0T7W2, HPRT_METLA
A2SPY9, HPRT_METLZA4G043, HPRT_METM5A9A8E9, HPRT_METM6
A6VID5, HPRT_METM7Q8PVT4, HPRT_METMAQ6M0X3, HPRT_METMP
D5E7U7, HPRT_METMSF8AJL1, HPRT_METOIB8GDM8, HPRT_METPE
D1YVK0, HPRT_METPSF6D512, HPRT_METPWD3DYU7, HPRT_METRM
D3S8C7, HPRT_METSFF4BT36, HPRT_METSGO27375, HPRT_METTH
O33174, HPRT_METTMA0B870, HPRT_METTPD7DQT8, HPRT_METV3
C9RH78, HPRT_METVMA6URC7, HPRT_METVSF7XQS2, HPRT_METZD
P00493, HPRT_MOUSEQ64531, HPRT_MUSSPA5A6I1, HPRT_PANTR
Q45FY6, HPRT_PIGP27605, HPRT_RATO33799, HPRT_SALTY
P09383, HPRT_SCHMAO13917, HPRT_SCHPOP0A9M4, HPRT_SHIFL
Q07010, HPRT_TRYBBP18134, HPRT_VIBHAQ04178, HPRT_YEAST
Q92F56, TILS_LISINQ724J4, TILS_LISMFQ8YAC7, TILS_LISMO

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