ID   2.4.99.18
DE   dolichyl-diphosphooligosaccharide--protein glycotransferase.
CA   a dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] =
CA   a dolichyl diphosphate + H(+) + N(4)-(oligosaccharide-(1->4)-N-acetyl-
CA   beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginy-
CA   [protein].
CC   -!- Occurs in eukaryotes that form a glycoprotein by the transfer of a
CC       glucosyl-mannosyl-glucosamine polysaccharide to the side-chain of an
CC       L-asparagine residue in the sequence -Asn-Xaa-Ser- or -Asn-Xaa-Thr-
CC       (Xaa not Pro) in nascent polypeptide chains.
CC   -!- The basic oligosaccharide is the tetradecasaccharide Glc3Man9GlcNAc2.
CC   -!- However, smaller oligosaccharides derived from it and
CC       oligosaccharides with additional monosaccharide units attached may be
CC       involved.
CC   -!- Man3GlcNAc2 seems to be common for all of the oligosaccharides
CC       involved with the terminal N-acetylglucosamine linked to the protein
CC       L-asparagine.
CC   -!- Occurs on the cytosolic face of the endoplasmic reticulum.
CC   -!- The dolichol involved normally has 14-21 isoprenoid units with two
CC       trans double-bonds at the omega end, and the rest of the double-bonds
CC       in cis form.
CC   -!- Formerly EC 2.4.1.119.
DR   Q93ZY3, STT3A_ARATH;  Q2KJI2, STT3A_BOVIN;  F1PJP5, STT3A_CANLF;
DR   P46977, STT3A_HUMAN;  P46978, STT3A_MOUSE;  Q6F2Z1, STT3A_ORYSJ;
DR   Q5RCE2, STT3A_PONAB;  Q9FX21, STT3B_ARATH;  E2RG47, STT3B_CANLF;
DR   Q8TCJ2, STT3B_HUMAN;  Q3TDQ1, STT3B_MOUSE;  Q7XQ88, STT3B_ORYSJ;
DR   P46975, STT3_CAEEL ;  Q54NM9, STT3_DICDI ;  O94335, STT3_SCHPO ;
DR   P39007, STT3_YEAST ;
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