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ENZYME

ENZYME entry: EC 2.4.99.25

Accepted Name
lipopolysaccharide heptosyltransferase III
Reaction catalysed
ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A <=> ADP + an L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)
Comment(s)
The enzyme catalyzes a glycosylation step in the biosynthesis of the inner core oligosaccharide of the lipopolysaccharide (endotoxin) of some Gram-negative bacteria.
Cross-references
BRENDA2.4.99.25
EC2PDB2.4.99.25
ExplorEnz2.4.99.25
PRIAM enzyme-specific profiles2.4.99.25
KEGG Ligand Database for Enzyme Nomenclature2.4.99.25
IUBMB Enzyme Nomenclature2.4.99.25
IntEnz2.4.99.25
MEDLINEFind literature relating to 2.4.99.25
MetaCyc2.4.99.25
Rhea expert-curated reactions2.4.99.25
UniProtKB/Swiss-Prot
P25742, WAAQ_ECOLIQ9R9D5, WAAQ_ECOLX

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