ID   2.4.99.27
DE   O-antigen polymerase Wzy.
AN   Wzy O-antigen polymerase.
AN   Wzy polymerase.
CA   n lipid-linked O-antigen repeat units = a lipid-linked O antigen + (n-1)
CA   polyisoprenyl diphosphate.
CC   -!- The Wzy-type polymerase polymerizes O antigen repeat unit
CC       oligosaccharides that are anchored to the periplasmic face of the
CC       inner membrane, forming an O antigen polysaccharide that is still
CC       anchored to the membrane.
CC   -!- A Wzz chain length regulator (sometimes referred to as an O-antigen
CC       co-polymerase) normally interacts with Wzy to confer a distinctive
CC       modal chain length distribution.
CC   -!- The resultant polysaccharide is transferred from the membrane anchor
CC       to the lipid A-core oligosaccharide by EC 2.4.99.26 forming a
CC       complete lipopolysaccharide structure.
CC   -!- There is an enormous diversity of O antigen polymerases with
CC       different specificities, reflecting the variability in the structure
CC       and composition of O-antigens.
DR   Q58YW1, WZY_ECOLX  ;  G3XCW3, WZY_PSEAE  ;  Q00474, WZY_SALMU  ;
DR   P0A236, WZY_SALTI  ;  P0A235, WZY_SALTY  ;  Q03584, WZY_SHIDY  ;
DR   P37784, WZY_SHIFL  ;
//