ENZYME entry: EC 2.4.99.4
| Accepted Name |
|---|
| Beta-galactoside alpha-2,3-sialyltransferase.
|
| Alternative Name(s) |
|---|
| CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase. |
| Reaction catalysed |
|---|
| CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R <=> CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R |
| Comment(s) |
|---|
- The acceptor is Gal-beta-1,3-GalNAc-R, where R is H, a threonine or
serine residue in a glycoprotein, or a glycolipid.
- Lactose can also act as acceptor.
- May be identical with EC 2.4.99.2.
|
| Cross-references |
|---|
| BRENDA | 2.4.99.4 |
| EC2PDB | 2.4.99.4 |
| ExplorEnz | 2.4.99.4 |
| PRIAM enzyme-specific profiles | 2.4.99.4 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.99.4 |
| IUBMB Enzyme Nomenclature | 2.4.99.4 |
| IntEnz | 2.4.99.4 |
| MEDLINE | Find literature relating to 2.4.99.4 |
| MetaCyc | 2.4.99.4 |
| UniProtKB/Swiss-Prot |
| Q11200, SIA4A_CHICK; | Q11201, SIA4A_HUMAN; | P54751, SIA4A_MOUSE; |
| Q6KB59, SIA4A_PANTR; | Q02745, SIA4A_PIG; | Q16842, SIA4B_HUMAN; |
| Q11204, SIA4B_MOUSE; | Q6KB58, SIA4B_PANTR; | Q11205, SIA4B_RAT; |
| Q11206, SIA4C_HUMAN; | Q91Y74, SIA4C_MOUSE; | P61130, SIA4C_PANTR; |
| P61131, SIA4C_RAT; |
|
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