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ENZYME entry: EC 2.4.99.4
Accepted Name |
beta-galactoside alpha-2,3-sialyltransferase.
|
Alternative Name(s) |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase. |
Reaction catalysed |
a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate <=> an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+) |
Comment(s) |
- The acceptor is Gal-beta-1,3-GalNAc-R, where R is H, a threonine or
serine residue in a glycoprotein, or a glycolipid.
- Lactose can also act as acceptor.
- May be identical with EC 2.4.99.2.
|
Cross-references |
BRENDA | 2.4.99.4 |
EC2PDB | 2.4.99.4 |
ExplorEnz | 2.4.99.4 |
PRIAM enzyme-specific profiles | 2.4.99.4 |
KEGG Ligand Database for Enzyme Nomenclature | 2.4.99.4 |
IUBMB Enzyme Nomenclature | 2.4.99.4 |
IntEnz | 2.4.99.4 |
MEDLINE | Find literature relating to 2.4.99.4 |
MetaCyc | 2.4.99.4 |
Rhea expert-curated reactions | 2.4.99.4 |
UniProtKB/Swiss-Prot |
Q11200, SIA4A_CHICK; | Q11201, SIA4A_HUMAN; | P54751, SIA4A_MOUSE; |
Q6KB59, SIA4A_PANTR; | Q02745, SIA4A_PIG; | Q16842, SIA4B_HUMAN; |
Q11204, SIA4B_MOUSE; | Q6KB58, SIA4B_PANTR; | Q11205, SIA4B_RAT; |
Q11206, SIA4C_HUMAN; | Q91Y74, SIA4C_MOUSE; | P61130, SIA4C_PANTR; |
P61131, SIA4C_RAT; |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.4.99.-
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