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ENZYME

ENZYME entry: EC 2.5.1.10

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.10
Accepted Name
(2E,6E)-farnesyl diphosphate synthase
Alternative Name(s)
farnesyl-diphosphate synthase
farnesyl pyrophosphate synthetase
FPP synthetase
geranyltranstransferase
Reaction catalysed
isopentenyl diphosphate + (2E)-geranyl diphosphate = (2E,6E)-farnesyl diphosphate + diphosphate
Comment(s)
  • Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate.
  • The enzyme will not accept larger prenyl diphosphates as efficient donors.
Cross-references
BRENDA2.5.1.10
EC2PDB2.5.1.10
ExplorEnz2.5.1.10
KEGG Ligand Database for Enzyme Nomenclature2.5.1.10
IUBMB Enzyme Nomenclature2.5.1.10
MEDLINEFind literature relating to 2.5.1.10
MetaCyc2.5.1.10
Rhea expert-curated reactions2.5.1.10
UniProtKB/Swiss-Prot
W6JPP9, AMYG_PHOAMQ672V6, ATMG_ASPFLA0A3S5XFG0, CLE6_ASPVE
B1XJV9, CRTE_PICP2P9WEX3, DPASD_APISAH1VQB1, DPCHD_COLHI
I1RL14, DPFGD_GIBZEP9WEX9, DPMAD_METANP9WEW8, DPMPD_MACPH
Q4WEB8, ERG20_ASPFUA0A1D8PH78, ERG20_CANALB4YA15, ERG20_GANLU
V6RG22, ERG20_GIBZEO14230, ERG20_SCHPOP08524, ERG20_YEAST
A0A1V0QSA8, ERIE_HERERA0A8D5M3Y5, ESDPD_PENSHQ09152, FPPS1_ARATH
Q7XYS9, FPPS1_ARTSIA0A7J6HWR9, FPPS1_CANSAP49351, FPPS1_LUPAL
O24241, FPPS1_PARARQ43315, FPPS2_ARATHQ7XYT0, FPPS2_ARTSI
A0A1V0QSH7, FPPS2_CANSAP49352, FPPS2_LUPALO24242, FPPS2_PARAR
P49350, FPPS_ARTANQ8WMY2, FPPS_BOVINP08836, FPPS_CHICK
Q92235, FPPS_FUSFUO64905, FPPS_HELANP14324, FPPS_HUMAN
P49349, FPPS_KLULAP49353, FPPS_MAIZEQ920E5, FPPS_MOUSE
A0A343W970, FPPS_MURHIP0A5H9, FPPS_MYCBOP9WKH0, FPPS_MYCTO
P9WKH1, FPPS_MYCTUQ92250, FPPS_NEUCRP05369, FPPS_RAT
Q9NH03, FPS_DICDIQ4JHN6, FPS_PANGIS0E627, GA5_GIBF5
O53507, GFPPS_MYCTUA0A858E6N7, GGDPS_MELLIA0A858E7G0, GGDPS_MELLP
P34802, GGPP1_ARATHO04046, GGPP2_ARATHQ9LUD9, GGPP3_ARATH
Q9SLG2, GGPP4_ARATHO22043, GGPP6_ARATHQ9ZU77, GGPP7_ARATH
Q9LRR0, GGPP8_ARATHQ9LUE1, GGPP9_ARATHQ9LJY2, GGPPA_ARATH
Q9LIA0, GGPPB_ARATHQ9LHR4, GGPPC_ARATHP56966, GGPPS_BOVIN
P80042, GGPPS_CAPANQ42698, GGPPS_CATROQ54BK1, GGPPS_DICDI
Q758K0, GGPPS_EREGSQ92236, GGPPS_FUSFUA0A0A7GEY4, GGPPS_GEOAI
Q94ID7, GGPPS_HEVBRO95749, GGPPS_HUMANQ9WTN0, GGPPS_MOUSE
Q9P885, GGPPS_MUCCLP24322, GGPPS_NEUCRQ6F596, GGPPS_RAT
O59703, GGPPS_SCHPOQ43133, GGPPS_SINALQ12051, GGPPS_YEAST
A0A2I6PJ05, GGS1_HYPPIB2DBE8, GGS1_PHOAMF9WWF1, GGS2_ZYMTI
F9XLC1, GGS3_ZYMTIB2DBE9, GGS4_PHOAMQ6F5E6, GGS_NEOBT
F9WZD2, GSS1_ZYMTIJ7FIX8, IDTG_CLAPAO66952, ISPA_AQUAE
P54383, ISPA_BACSUQ45220, ISPA_BRADUP57537, ISPA_BUCAI
Q8K9A0, ISPA_BUCAPP22939, ISPA_ECOLIQ08291, ISPA_GEOSE
P45204, ISPA_HAEINO66126, ISPA_MICLUP55539, ISPA_SINFN
A0A0E3D8M9, JANG_PENJAQ56RZ3, LTMG_EPIFFQ56RZ7, LTMG_EPIFI
O06428, NPPPS_MYCTUP9WEQ2, OLCC_PENCNQ9C446, PAXG_PENPX
A0A1U8QLG8, PBCB_EMENIA0A0E3D8P4, PENG_PENCRA0A2L0VXR5, PLE4_CLIPA
A0A6S6QJ62, PLE4_RHOPPA0A140JWS2, PTMG_PENOHA0A1B4XBK0, SDNC_SORAA
Q4WBI4, SPYE_ASPFUE9F5E9, SUBD_METRAQ65164, TPRT_ASFB7
P0C9E2, TPRT_ASFK5Q8V9T7, TPRT_ASFM2P0C9E0, TPRT_ASFP4
P0C9E1, TPRT_ASFWAP9WEF2, VNIC_VIRNID7PHZ5, VRTD_PENAE
Q55EU7, Y8742_DICDIQ54XP1, Y8823_DICDI

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-