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ENZYME entry: EC 2.5.1.10

Accepted Name
(2E,6E)-farnesyl diphosphate synthase.
Alternative Name(s)
Farnesyl pyrophosphate synthetase.
Farnesyl-diphosphate synthase.
FPP synthetase.
Geranyltranstransferase.
Reaction catalysed
Geranyl diphosphate + isopentenyl diphosphate <=> diphosphate + (2E,6E)-farnesyl diphosphate
Comment(s)
  • Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate.
  • The enzyme will not accept larger prenyl diphosphates as efficient donors.
Cross-references
PROSITEPDOC00407
BRENDA2.5.1.10
EC2PDB2.5.1.10
ExplorEnz2.5.1.10
PRIAM enzyme-specific profiles2.5.1.10
KEGG Ligand Database for Enzyme Nomenclature2.5.1.10
IUBMB Enzyme Nomenclature2.5.1.10
IntEnz2.5.1.10
MEDLINEFind literature relating to 2.5.1.10
MetaCyc2.5.1.10
UniProtKB/Swiss-Prot
Q672V6, ATMG_ASPFL;  P9WEX3, DPASD_ARTSH;  H1VQB1, DPCHD_COLHI;  
I1RL14, DPFGD_GIBZE;  P9WEX9, DPMAD_METAN;  P9WEW8, DPMPD_MACPH;  
Q09152, FPPS1_ARATH;  Q7XYS9, FPPS1_ARTSI;  P49351, FPPS1_LUPAL;  
O24241, FPPS1_PARAR;  Q43315, FPPS2_ARATH;  Q7XYT0, FPPS2_ARTSI;  
P49352, FPPS2_LUPAL;  O24242, FPPS2_PARAR;  P49350, FPPS_ARTAN;  
Q8WMY2, FPPS_BOVIN;  P08836, FPPS_CHICK;  Q92235, FPPS_GIBFU;  
O64905, FPPS_HELAN;  P14324, FPPS_HUMAN;  P49349, FPPS_KLULA;  
P49353, FPPS_MAIZE;  Q920E5, FPPS_MOUSE;  P0A5H9, FPPS_MYCBO;  
P9WKH0, FPPS_MYCTO;  P9WKH1, FPPS_MYCTU;  Q92250, FPPS_NEUCR;  
P05369, FPPS_RAT;  O14230, FPPS_SCHPO;  P08524, FPPS_YEAST;  
Q9NH03, FPS_DICDI;  Q4JHN6, FPS_PANGI;  S0E627, GA5_GIBF5;  
O53507, GFPPS_MYCTU;  P34802, GGPP1_ARATH;  O04046, GGPP2_ARATH;  
Q9LUD9, GGPP3_ARATH;  Q9SLG2, GGPP4_ARATH;  O22043, GGPP6_ARATH;  
Q9ZU77, GGPP7_ARATH;  Q9LRR0, GGPP8_ARATH;  Q9LUE1, GGPP9_ARATH;  
Q9LJY2, GGPPA_ARATH;  Q9LIA0, GGPPB_ARATH;  Q9LHR4, GGPPC_ARATH;  
Q758K0, GGPPS_ASHGO;  P56966, GGPPS_BOVIN;  P80042, GGPPS_CAPAN;  
Q42698, GGPPS_CATRO;  Q54BK1, GGPPS_DICDI;  A0A0A7GEY4, GGPPS_GEOAI;  
Q92236, GGPPS_GIBFU;  Q94ID7, GGPPS_HEVBR;  O95749, GGPPS_HUMAN;  
Q9WTN0, GGPPS_MOUSE;  Q9P885, GGPPS_MUCCL;  P24322, GGPPS_NEUCR;  
Q6F596, GGPPS_RAT;  O59703, GGPPS_SCHPO;  Q43133, GGPPS_SINAL;  
Q12051, GGPPS_YEAST;  A0A2L0VXR5, GGPS_CLIPA;  A0A2I6PJ05, GGS1_HYPPI;  
B2DBE8, GGS1_PHOAM;  F9WWF1, GGS2_ZYMTI;  F9XLC1, GGS3_ZYMTI;  
B2DBE9, GGS4_PHOAM;  Q6F5E6, GGS_PLEBE;  F9WZD2, GSS1_ZYMTI;  
J7FIX8, IDTG_CLAPA;  O66952, ISPA_AQUAE;  P54383, ISPA_BACSU;  
Q45220, ISPA_BRADU;  P57537, ISPA_BUCAI;  Q8K9A0, ISPA_BUCAP;  
P22939, ISPA_ECOLI;  Q08291, ISPA_GEOSE;  P45204, ISPA_HAEIN;  
O66126, ISPA_MICLU;  P55539, ISPA_SINFN;  A0A0E3D8M9, JANG_PENJA;  
Q56RZ3, LTMG_EPIFF;  Q56RZ7, LTMG_EPIFI;  O06428, NPPPS_MYCTU;  
Q9C446, PAXG_PENPX;  A0A1U8QLG8, PBCB_EMENI;  A0A0E3D8P4, PENG_PENCR;  
A0A140JWS2, PTMG_PENSI;  A0A1B4XBK0, SDNC_SORAA;  E9F5E9, SUBD_METRA;  
Q65164, TPRT_ASFB7;  P0C9E2, TPRT_ASFK5;  Q8V9T7, TPRT_ASFM2;  
P0C9E0, TPRT_ASFP4;  P0C9E1, TPRT_ASFWA;  D7PHZ5, VRTD_PENAE;  
Q55EU7, Y8742_DICDI;  Q54XP1, Y8823_DICDI;  

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