ENZYME entry: EC 2.5.1.10

Accepted Name

(2E,6E)-farnesyl diphosphate synthase

Alternative Name(s)

farnesyl-diphosphate synthase

farnesyl pyrophosphate synthetase

FPP synthetase

geranyltranstransferase

Reaction catalysed

(2E)-geranyl diphosphate + isopentenyl diphosphate = (2E,6E)-farnesyl diphosphate + diphosphate

Comment(s)

Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate.
The enzyme will not accept larger prenyl diphosphates as efficient donors.

Cross-references

BRENDA

2.5.1.10

EC2PDB

2.5.1.10

ExplorEnz

2.5.1.10

PRIAM enzyme-specific profiles

2.5.1.10

KEGG Ligand Database for Enzyme Nomenclature

2.5.1.10

IUBMB Enzyme Nomenclature

2.5.1.10

IntEnz

2.5.1.10

MEDLINE

Find literature relating to 2.5.1.10

MetaCyc

2.5.1.10

Rhea expert-curated reactions

2.5.1.10

UniProtKB/Swiss-Prot

Q672V6, ATMG_ASPFL	B1XJV9, CRTE_PICP2	P9WEX3, DPASD_APISA
H1VQB1, DPCHD_COLHI	I1RL14, DPFGD_GIBZE	P9WEX9, DPMAD_METAN
P9WEW8, DPMPD_MACPH	Q4WEB8, ERG20_ASPFU	A0A1D8PH78, ERG20_CANAL
B4YA15, ERG20_GANLU	V6RG22, ERG20_GIBZE	O14230, ERG20_SCHPO
P08524, ERG20_YEAST	A0A1V0QSA8, ERIE_HERER	Q09152, FPPS1_ARATH
Q7XYS9, FPPS1_ARTSI	P49351, FPPS1_LUPAL	O24241, FPPS1_PARAR
Q43315, FPPS2_ARATH	Q7XYT0, FPPS2_ARTSI	P49352, FPPS2_LUPAL
O24242, FPPS2_PARAR	P49350, FPPS_ARTAN	Q8WMY2, FPPS_BOVIN
P08836, FPPS_CHICK	Q92235, FPPS_GIBFU	O64905, FPPS_HELAN
P14324, FPPS_HUMAN	P49349, FPPS_KLULA	P49353, FPPS_MAIZE
Q920E5, FPPS_MOUSE	A0A343W970, FPPS_MURHI	P0A5H9, FPPS_MYCBO
P9WKH0, FPPS_MYCTO	P9WKH1, FPPS_MYCTU	Q92250, FPPS_NEUCR
P05369, FPPS_RAT	Q9NH03, FPS_DICDI	Q4JHN6, FPS_PANGI
S0E627, GA5_GIBF5	O53507, GFPPS_MYCTU	A0A858E6N7, GGDPS_MELLI
A0A858E7G0, GGDPS_MELLP	P34802, GGPP1_ARATH	O04046, GGPP2_ARATH
Q9LUD9, GGPP3_ARATH	Q9SLG2, GGPP4_ARATH	O22043, GGPP6_ARATH
Q9ZU77, GGPP7_ARATH	Q9LRR0, GGPP8_ARATH	Q9LUE1, GGPP9_ARATH
Q9LJY2, GGPPA_ARATH	Q9LIA0, GGPPB_ARATH	Q9LHR4, GGPPC_ARATH
P56966, GGPPS_BOVIN	P80042, GGPPS_CAPAN	Q42698, GGPPS_CATRO
Q54BK1, GGPPS_DICDI	Q758K0, GGPPS_EREGS	A0A0A7GEY4, GGPPS_GEOAI
Q92236, GGPPS_GIBFU	Q94ID7, GGPPS_HEVBR	O95749, GGPPS_HUMAN
Q9WTN0, GGPPS_MOUSE	Q9P885, GGPPS_MUCCL	P24322, GGPPS_NEUCR
Q6F596, GGPPS_RAT	O59703, GGPPS_SCHPO	Q43133, GGPPS_SINAL
Q12051, GGPPS_YEAST	A0A2I6PJ05, GGS1_HYPPI	B2DBE8, GGS1_PHOAM
F9WWF1, GGS2_ZYMTI	F9XLC1, GGS3_ZYMTI	B2DBE9, GGS4_PHOAM
Q6F5E6, GGS_NEOBT	F9WZD2, GSS1_ZYMTI	J7FIX8, IDTG_CLAPA
O66952, ISPA_AQUAE	P54383, ISPA_BACSU	Q45220, ISPA_BRADU
P57537, ISPA_BUCAI	Q8K9A0, ISPA_BUCAP	P22939, ISPA_ECOLI
Q08291, ISPA_GEOSE	P45204, ISPA_HAEIN	O66126, ISPA_MICLU
P55539, ISPA_SINFN	A0A0E3D8M9, JANG_PENJA	Q56RZ3, LTMG_EPIFF
Q56RZ7, LTMG_EPIFI	O06428, NPPPS_MYCTU	P9WEQ2, OLCC_PENCN
Q9C446, PAXG_PENPX	A0A1U8QLG8, PBCB_EMENI	A0A0E3D8P4, PENG_PENCR
A0A2L0VXR5, PLE4_CLIPA	A0A6S6QJ62, PLE4_RHOPP	A0A140JWS2, PTMG_PENSI
A0A1B4XBK0, SDNC_SORAA	E9F5E9, SUBD_METRA	Q65164, TPRT_ASFB7
P0C9E2, TPRT_ASFK5	Q8V9T7, TPRT_ASFM2	P0C9E0, TPRT_ASFP4
P0C9E1, TPRT_ASFWA	D7PHZ5, VRTD_PENAE	Q55EU7, Y8742_DICDI
Q54XP1, Y8823_DICDI

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