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ENZYME entry: EC 2.5.1.106

Accepted Name
tryprostatin B synthase.
Alternative Name(s)
brevianamide F prenyltransferase.
Reaction catalysed
brevianamide F + dimethylallyl diphosphate <=> diphosphate + tryprostatin B
Comment(s)
  • The enzyme from the fungus Aspergillus fumigatus can also prenylate other tryptophan-containing cyclic dipeptides.
  • Prenylation occurs mainly at C-2, but also at C-3.
  • Involved in the biosynthetic pathways of several indole alkaloids such as tryprostatins, cyclotryprostatins, spirotryprostatins, fumitremorgins and verruculogen.
Cross-references
BRENDA2.5.1.106
EC2PDB2.5.1.106
ExplorEnz2.5.1.106
PRIAM enzyme-specific profiles2.5.1.106
KEGG Ligand Database for Enzyme Nomenclature2.5.1.106
IUBMB Enzyme Nomenclature2.5.1.106
IntEnz2.5.1.106
MEDLINEFind literature relating to 2.5.1.106
MetaCyc2.5.1.106
Rhea expert-curated reactions2.5.1.106
UniProtKB/Swiss-Prot
B9WZX3, FTMB_ASPFM;  Q4WAW7, FTMB_ASPFU;  A1DA62, FTMB_NEOFI;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
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