Expasy logo

ENZYME

ENZYME entry: EC 2.5.1.113

Accepted Name
[CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
Alternative Name(s)
CysO-thiocarboxylate-dependent cysteine synthase
Reaction catalysed
[CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + O-phospho-L-serine <=> [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-Cys + phosphate
Comment(s)
  • The enzyme participates in an alternative pathway for L-cysteine biosynthesis that involves a protein-bound thiocarboxylate as the sulfide donor.
  • The enzyme from the bacterium Mycobacterium tuberculosis also has very low activity with O(3)-acetyl-L-serine (cf. EC 2.5.1.65).
  • Formerly EC 2.5.1.n5.
Cross-references
BRENDA2.5.1.113
EC2PDB2.5.1.113
ExplorEnz2.5.1.113
PRIAM enzyme-specific profiles2.5.1.113
KEGG Ligand Database for Enzyme Nomenclature2.5.1.113
IUBMB Enzyme Nomenclature2.5.1.113
IntEnz2.5.1.113
MEDLINEFind literature relating to 2.5.1.113
MetaCyc2.5.1.113
Rhea expert-curated reactions2.5.1.113
UniProtKB/Swiss-Prot
P63874, CYSM_MYCBOP9WP52, CYSM_MYCTOP9WP53, CYSM_MYCTU

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-