ID 2.5.1.127 DE caldopentamine synthase. AN long-chain polyamine synthase. CA norspermine + S-adenosyl 3-(methylsulfanyl)propylamine = caldopentamine + CA 2 H(+) + S-methyl-5'-thioadenosine. CC -!- The enzyme, characterized from the thermophilic archaeon Hyperthermus CC butylicus, can also synthesize norspermine from norspermidine and CC thermospermine from spermidine (with lower activity). CC -!- The long-chain polyamines stabilize double-stranded DNA at high CC temperatures. CC -!- In contrast to EC 2.5.1.23 and EC 2.5.1.126, this enzyme shows no CC activity with propane-1,3-diamine. DR A2BIX4, SPEE1_HYPBU; //