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ENZYME entry: EC 2.5.1.138

Accepted Name
Coumarin 8-geranyltransferase.
Reaction catalysed
  • Geranyl diphosphate + umbelliferone <=> diphosphate + 8-geranylumbelliferone
  • Geranyl diphosphate + esculetin <=> diphosphate + 8-geranylesculetin
Comment(s)
  • The enzyme, characterized from the plant Citrus limon, is specific for geranyl diphosphate as a prenyl donor.
  • It also has low activity with the coumarins 5,7-dihydroxycoumarin and 5-methoxy-7-hydroxycoumarin.
Cross-references
BRENDA2.5.1.138
EC2PDB2.5.1.138
ExplorEnz2.5.1.138
PRIAM enzyme-specific profiles2.5.1.138
KEGG Ligand Database for Enzyme Nomenclature2.5.1.138
IUBMB Enzyme Nomenclature2.5.1.138
IntEnz2.5.1.138
MEDLINEFind literature relating to 2.5.1.138
MetaCyc2.5.1.138
UniProtKB/Swiss-Prot
A0A077K8G3, CGT1A_CITLI;  A0A077K9K6, CGT1B_CITLI;  

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