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ENZYME

ENZYME entry: EC 2.5.1.148

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.148
Accepted Name
lycopaoctaene synthase
Reaction catalysed
2 (2E,6E,10E)-geranylgeranyl diphosphate + NADPH + H(+) = all-trans-lycopaoctaene + 2 diphosphate + NADP(+)
Comment(s)
  • The enzyme, characterized from the green microalga Botryococcus braunii race L, in involved in biosynthesis of (14E,18E)-lycopadiene.
  • In vitro, the enzyme can accept (2E,6E)-farnesyl diphosphate and phytyl diphosphate as substrates, and is also able to catalyze the condensation of two different substrate molecules, forming chimeric products.
  • However, the use of these alternative substrates is not significant in vivo.
Cross-references
Rhea expert-curated reactions2.5.1.148
ExplorEnz2.5.1.148
IUBMB Enzyme Nomenclature2.5.1.148
UniProtKB/Swiss-Prot
A0A142ZC57, LOS_BOTBR
BRENDA2.5.1.148
MetaCyc2.5.1.148
KEGG Ligand Database for Enzyme Nomenclature2.5.1.148
EC2PDB2.5.1.148
MEDLINEFind literature relating to 2.5.1.148

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