ID 2.5.1.156 DE geranylfarnesylglycerol-phosphate geranylfarnesyltransferase. AN 2,3-bis-O-(farnesylgeranyl)-sn-glycerol 1-phosphate synthase. AN 2,3-di-O-farnesylgeranylglyceryl synthase. AN DGFGP synthase. CA (2E,6E,10E,14E)-geranylfarnesyl diphosphate + sn-3- CA (O-farnesylgeranyl)glycerol 1-phosphate = 2,3-bis-O-(geranylfarnesyl)- CA sn-glycerol 1-phosphate + diphosphate. CC -!- The enzyme, characterized from the archaeon Aeropyrum pernix, carries CC out the second prenyltransfer reaction involved in the formation of CC C25,C25 membrane diether-lipids in some archaea. CC -!- Requires a divalent metal cation, such as Mg(2+). CC -!- The enzyme cannot accept sn-3-(O-geranylgeranyl)glycerol 1-phosphate CC as the prenyl donor. cf. EC 2.5.1.42. //