ENZYME entry: EC 2.5.1.29

Accepted Name

geranylgeranyl diphosphate synthase

Alternative Name(s)

farnesyltransferase

farnesyltranstransferase

geranylgeranyl-diphosphate synthase

geranylgeranyl-PP synthetase

geranylgeranyl pyrophosphate synthase

geranylgeranyl pyrophosphate synthetase

Reaction catalysed

(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + diphosphate

Comment(s)

Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.

Cross-references

BRENDA

2.5.1.29

EC2PDB

2.5.1.29

ExplorEnz

2.5.1.29

PRIAM enzyme-specific profiles

2.5.1.29

KEGG Ligand Database for Enzyme Nomenclature

2.5.1.29

IUBMB Enzyme Nomenclature

2.5.1.29

IntEnz

2.5.1.29

MEDLINE

Find literature relating to 2.5.1.29

MetaCyc

2.5.1.29

Rhea expert-curated reactions

2.5.1.29

UniProtKB/Swiss-Prot

A0A1L9UKS1, ABVS_ASPBC	Q672V6, ATMG_ASPFL	P9WEP0, AUAS_ASPUT
C9K2Q3, BSC8_ALTBR	N4V6D4, BTCA_COLOR	A0A2Z6FZ31, BTCA_NEOBT
P9WEV7, CGDS_COLGL	P54976, CRTE_CERS4	P48368, CRTE_CYAPA
P21684, CRTE_PANAN	B1XJV9, CRTE_PICP2	P22873, CRTE_PSEVU
P17060, CRTE_RHOCB	P9WEX3, DPASD_APISA	H1VQB1, DPCHD_COLHI
I1RL14, DPFGD_GIBZE	P9WEX9, DPMAD_METAN	P9WEW8, DPMPD_MACPH
A0A1V0QSA8, ERIE_HERER	A0A169T193, EVAS_EMEVA	A0A0P0ZD79, EVVS_EMEVA
A2PZA5, FC1_PHOAM	A0A1L7VFX3, FUP1_FUSPR	S0E627, GA5_GIBF5
A0A858E6N7, GGDPS_MELLI	A0A858E7G0, GGDPS_MELLP	P34802, GGPP1_ARATH
O04046, GGPP2_ARATH	Q9LUD9, GGPP3_ARATH	Q9SLG2, GGPP4_ARATH
O22043, GGPP6_ARATH	Q9ZU77, GGPP7_ARATH	Q9LRR0, GGPP8_ARATH
Q9LUE1, GGPP9_ARATH	Q9LJY2, GGPPA_ARATH	Q9LIA0, GGPPB_ARATH
Q9LHR4, GGPPC_ARATH	P56966, GGPPS_BOVIN	P80042, GGPPS_CAPAN
Q42698, GGPPS_CATRO	Q54BK1, GGPPS_DICDI	Q758K0, GGPPS_EREGS
A0A0A7GEY4, GGPPS_GEOAI	Q92236, GGPPS_GIBFU	Q94ID7, GGPPS_HEVBR
O95749, GGPPS_HUMAN	Q9WTN0, GGPPS_MOUSE	Q9P885, GGPPS_MUCCL
O50410, GGPPS_MYCTU	P24322, GGPPS_NEUCR	Q6F596, GGPPS_RAT
O59703, GGPPS_SCHPO	Q43133, GGPPS_SINAL	Q12051, GGPPS_YEAST
Q8PW34, GGPP_METMA	P95999, GGPS_SACS2	P39464, GGPS_SULAC
A0A2I6PJ05, GGS1_HYPPI	B2DBE8, GGS1_PHOAM	F9WWF1, GGS2_ZYMTI
F9XLC1, GGS3_ZYMTI	B2DBE9, GGS4_PHOAM	Q6F5E6, GGS_NEOBT
F9WZD2, GSS1_ZYMTI	J7FIX8, IDTG_CLAPA	A0A0E3D8M9, JANG_PENJA
Q56RZ3, LTMG_EPIFF	Q56RZ7, LTMG_EPIFI	A1DN30, NFSS_NEOFI
O06428, NPPPS_MYCTU	A0A0U5G0B1, OBLA_ASPCI	A1C8C3, OBLA_ASPCL
M2V8C1, OBLA_COCH5	A0A1V1FVQ6, OBLA_EMEVA	P9WEQ2, OLCC_PENCN
P9WEV6, PAPS_PHOAM	Q9C446, PAXG_PENPX	A0A1U8QLG8, PBCB_EMENI
A0A2Z6AQX7, PBSS_PENBI	A0A348DU52, PCCS_PENCH	B6HFX8, PCHDS_PENRW
A0A0E3D8P4, PENG_PENCR	A0A2L0VXR5, PLE4_CLIPA	A0A6S6QJ62, PLE4_RHOPP
W6QAE7, PRDS_PENRF	A0A140JWS2, PTMG_PENSI	A0A348FUE1, PVCPS_TALVE
A0A2Z6AQX6, PVPS_TALVE	A0A1Y1C7Q5, QNN1_EMEVA	A0A1B4XBK0, SDNC_SORAA
Q8S948, SPS1_ARATH	E9F5E9, SUBD_METRA	A0A8K1AY78, TNDC_ASPFV
M2U578, TPCA_COCH5	Q65164, TPRT_ASFB7	P0C9E2, TPRT_ASFK5
Q8V9T7, TPRT_ASFM2	P0C9E0, TPRT_ASFP4	P0C9E1, TPRT_ASFWA

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