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ENZYME

ENZYME entry: EC 2.5.1.29

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.29
Accepted Name
geranylgeranyl diphosphate synthase
Alternative Name(s)
farnesyltransferase
farnesyltranstransferase
geranylgeranyl-diphosphate synthase
geranylgeranyl-PP synthetase
geranylgeranyl pyrophosphate synthase
geranylgeranyl pyrophosphate synthetase
Reaction catalysed
isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + diphosphate
Comment(s)
Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.
Cross-references
BRENDA2.5.1.29
EC2PDB2.5.1.29
ExplorEnz2.5.1.29
KEGG Ligand Database for Enzyme Nomenclature2.5.1.29
IUBMB Enzyme Nomenclature2.5.1.29
MEDLINEFind literature relating to 2.5.1.29
MetaCyc2.5.1.29
Rhea expert-curated reactions2.5.1.29
UniProtKB/Swiss-Prot
A0A1L9UKS1, ABVS_ASPBCQ672V6, ATMG_ASPFLP9WEP0, AUAS_ASPUT
C9K2Q3, BSC8_ALTBRN4V6D4, BTCA_COLORA0A2Z6FZ31, BTCA_NEOBT
P9WEV7, CGDS_COLGLA0A3S5XFG0, CLE6_ASPVEP54976, CRTE_CERS4
P48368, CRTE_CYAPAP21684, CRTE_PANANB1XJV9, CRTE_PICP2
P22873, CRTE_PSEVUP17060, CRTE_RHOCBP9WEX3, DPASD_APISA
H1VQB1, DPCHD_COLHII1RL14, DPFGD_GIBZEP9WEX9, DPMAD_METAN
P9WEW8, DPMPD_MACPHA0A1V0QSA8, ERIE_HERERA0A8D5M3Y5, ESDPD_PENSH
A0A169T193, EVAS_EMEVAA0A0P0ZD79, EVVS_EMEVAA2PZA5, FC1_PHOAM
A0A1L7VFX3, FUP1_FUSPRS0E627, GA5_GIBF5A0A858E6N7, GGDPS_MELLI
A0A858E7G0, GGDPS_MELLPP34802, GGPP1_ARATHO04046, GGPP2_ARATH
Q9LUD9, GGPP3_ARATHQ9SLG2, GGPP4_ARATHO22043, GGPP6_ARATH
Q9ZU77, GGPP7_ARATHQ9LRR0, GGPP8_ARATHQ9LUE1, GGPP9_ARATH
Q9LJY2, GGPPA_ARATHQ9LIA0, GGPPB_ARATHQ9LHR4, GGPPC_ARATH
P56966, GGPPS_BOVINP80042, GGPPS_CAPANQ42698, GGPPS_CATRO
Q54BK1, GGPPS_DICDIQ758K0, GGPPS_EREGSQ92236, GGPPS_FUSFU
A0A0A7GEY4, GGPPS_GEOAIQ94ID7, GGPPS_HEVBRO95749, GGPPS_HUMAN
Q9WTN0, GGPPS_MOUSEQ9P885, GGPPS_MUCCLO50410, GGPPS_MYCTU
P24322, GGPPS_NEUCRQ6F596, GGPPS_RATO59703, GGPPS_SCHPO
Q43133, GGPPS_SINALQ12051, GGPPS_YEASTQ8PW34, GGPP_METMA
P95999, GGPS_SACS2P39464, GGPS_SULACA0A2I6PJ05, GGS1_HYPPI
B2DBE8, GGS1_PHOAMF9WWF1, GGS2_ZYMTIF9XLC1, GGS3_ZYMTI
B2DBE9, GGS4_PHOAMQ6F5E6, GGS_NEOBTF9WZD2, GSS1_ZYMTI
J7FIX8, IDTG_CLAPAA0A0E3D8M9, JANG_PENJAQ56RZ3, LTMG_EPIFF
Q56RZ7, LTMG_EPIFIA1DN30, NFSS_NEOFIO06428, NPPPS_MYCTU
A0A0U5G0B1, OBLA_ASPCIA1C8C3, OBLA_ASPCLM2V8C1, OBLA_COCH5
A0A1V1FVQ6, OBLA_EMEVAP9WEQ2, OLCC_PENCNP9WEV6, PAPS_PHOAM
Q9C446, PAXG_PENPXA0A1U8QLG8, PBCB_EMENIA0A2Z6AQX7, PBSS_PENBI
A0A348DU52, PCCS_PENCHB6HFX8, PCHDS_PENRWA0A0E3D8P4, PENG_PENCR
A0A2L0VXR5, PLE4_CLIPAA0A6S6QJ62, PLE4_RHOPPW6QAE7, PRDS_PENRF
A0A140JWS2, PTMG_PENOHA0A348FUE1, PVCPS_TALVEA0A2Z6AQX6, PVPS_TALVE
A0A1Y1C7Q5, QNN1_EMEVAA0A1B4XBK0, SDNC_SORAAQ8S948, SPS1_ARATH
Q4WBI4, SPYE_ASPFUE9F5E9, SUBD_METRAA0A8K1AY78, TNDC_ASPFV
M2U578, TPCA_COCH5Q65164, TPRT_ASFB7P0C9E2, TPRT_ASFK5
Q8V9T7, TPRT_ASFM2P0C9E0, TPRT_ASFP4P0C9E1, TPRT_ASFWA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-