Expasy logo

ENZYME

ENZYME entry: EC 2.5.1.30

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.30
Accepted Name
heptaprenyl diphosphate synthase
Alternative Name(s)
all-trans-heptaprenyl-diphosphate synthase
HepPP synthase
heptaprenyl pyrophosphate synthetase
trans-hexaprenyltranstransferase
Reaction catalysed
4 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-heptaprenyl diphosphate + 4 diphosphate
Comment(s)
  • This enzyme catalyzes the condensation reactions resulting in the formation of all-trans-heptaprenyl diphosphate, the isoprenoid side chain of ubiquinone-7 and menaquinone-7.
  • The enzyme adds four isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry.
Cross-references
BRENDA2.5.1.30
EC2PDB2.5.1.30
ExplorEnz2.5.1.30
KEGG Ligand Database for Enzyme Nomenclature2.5.1.30
IUBMB Enzyme Nomenclature2.5.1.30
MEDLINEFind literature relating to 2.5.1.30
MetaCyc2.5.1.30
Rhea expert-curated reactions2.5.1.30
UniProtKB/Swiss-Prot
P31112, HEPS1_BACSUP55784, HEPS1_GEOSEP31114, HEPS2_BACSU
P55785, HEPS2_GEOSE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-