ID   2.5.1.48
DE   cystathionine gamma-synthase.
AN   cystathionine synthase.
AN   cystathionine synthetase.
AN   homoserine transsuccinylase.
AN   O-succinylhomoserine (thiol)-lyase.
AN   O-succinylhomoserine synthase.
AN   O-succinylhomoserine synthetase.
AN   O-succinyl-L-homoserine succinate-lyase (adding cysteine).
CA   O-succinyl-L-homoserine + L-cysteine = L,L-cystathionine + succinate +
CA   H(+).
CC   -!- Also reacts with H2S and methanethiol as replacing agents, producing
CC       homocysteine and methionine, respectively.
CC   -!- In the absence of thiol, can also catalyze beta,gamma-elimination to
CC       form 2-oxobutanoate, succinate and ammonia.
CC   -!- Formerly EC 4.2.99.9.
DR   P38675, MET7_NEUCR ;  O74314, MET7_SCHPO ;  P47164, MET7_YEAST ;
DR   P00935, METB_ECOLI ;  P44502, METB_HAEIN ;  Q9ZMW7, METB_HELPJ ;
DR   Q1M0P5, METB_HELPX ;  P56069, METB_HELPY ;  P24601, METB_HERAU ;
DR   P66876, METB_MYCBO ;  P46807, METB_MYCLE ;  P9WGB6, METB_MYCTO ;
DR   P9WGB7, METB_MYCTU ;  Q04533, METX_YEAST ;
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