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ENZYME entry: EC 2.5.1.57

Accepted Name
N-acylneuraminate-9-phosphate synthase.
Alternative Name(s)
N-acetylneuraminate 9-phosphate lyase.
N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase.
N-acetylneuraminate 9-phosphate synthetase.
N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating).
Sialic acid 9-phosphate synthetase.
Reaction catalysed
Phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate + H(2)O <=> N-acylneuraminate 9-phosphate + phosphate
Comment(s)
  • Acts on N-glycoloyl and N-acetyl-derivatives.
  • Formerly EC 4.1.3.20.
Cross-references
BRENDA2.5.1.57
EC2PDB2.5.1.57
ExplorEnz2.5.1.57
PRIAM enzyme-specific profiles2.5.1.57
KEGG Ligand Database for Enzyme Nomenclature2.5.1.57
IUBMB Enzyme Nomenclature2.5.1.57
IntEnz2.5.1.57
MEDLINEFind literature relating to 2.5.1.57
MetaCyc2.5.1.57
Rhea expert-curated reactions2.5.1.57
UniProtKB/Swiss-Prot
Q9VG74, SIAS_DROME;  Q9NR45, SIAS_HUMAN;  Q99J77, SIAS_MOUSE;  

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