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ENZYME entry: EC 2.5.1.66

Accepted Name
N(2)-(2-carboxyethyl)arginine synthase.
Alternative Name(s)
CEAS.
CEA synthetase.
N(2)-(2-carboxyethyl)arginine synthetase.
Reaction catalysed
D-glyceraldehyde 3-phosphate + L-arginine <=> H(+) + N(2)-(2-carboxyethyl)-L-arginine + phosphate
Comment(s)
  • Requires thiamine diphosphate and catalyzes the first step in the clavulanic-acid biosynthesis pathway.
  • The 2-hydroxy-3-oxo group transferred from glyceraldehyde 3-phosphate is isomerized during transfer to form the 2-carboxyethyl group.
Cross-references
BRENDA2.5.1.66
EC2PDB2.5.1.66
ExplorEnz2.5.1.66
PRIAM enzyme-specific profiles2.5.1.66
KEGG Ligand Database for Enzyme Nomenclature2.5.1.66
IUBMB Enzyme Nomenclature2.5.1.66
IntEnz2.5.1.66
MEDLINEFind literature relating to 2.5.1.66
MetaCyc2.5.1.66
Rhea expert-curated reactions2.5.1.66
UniProtKB/Swiss-Prot
Q9LCV9, CEAS_STRCL

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-