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ENZYME

ENZYME entry: EC 2.5.1.68

Accepted Name
(2Z,6E)-farnesyl diphosphate synthase
Alternative Name(s)
(Z)-farnesyl diphosphate synthase
Z-farnesyl diphosphate synthase
Reaction catalysed
(2E)-geranyl diphosphate + isopentenyl diphosphate <=> (2Z,6E)-farnesyl diphosphate + diphosphate
Comment(s)
  • The product of this reaction is an intermediate in the synthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of most features of the mycobacterial cell wall, including peptidoglycan, linker unit galactan and arabinan.
  • Neryl diphosphate can also act as substrate.
Cross-references
BRENDA2.5.1.68
EC2PDB2.5.1.68
ExplorEnz2.5.1.68
PRIAM enzyme-specific profiles2.5.1.68
KEGG Ligand Database for Enzyme Nomenclature2.5.1.68
IUBMB Enzyme Nomenclature2.5.1.68
IntEnz2.5.1.68
MEDLINEFind literature relating to 2.5.1.68
MetaCyc2.5.1.68
Rhea expert-curated reactions2.5.1.68
UniProtKB/Swiss-Prot
A0A386JVA3, FPPS_NEZVIQ7U0P8, ZFPP_MYCBOQ9CB36, ZFPP_MYCLE
A0R2W4, ZFPP_MYCS2P9WFF4, ZFPP_MYCTOP9WFF5, ZFPP_MYCTU
Q47SS3, ZFPP_THEFY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-