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ENZYME

ENZYME entry: EC 2.5.1.78

Accepted Name
6,7-dimethyl-8-ribityllumazine synthase
Alternative Name(s)
lumazine synthase
Reaction catalysed
(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil <=> 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate
Comment(s)
Involved in riboflavin biosynthesis.
Cross-references
BRENDA2.5.1.78
EC2PDB2.5.1.78
ExplorEnz2.5.1.78
PRIAM enzyme-specific profiles2.5.1.78
KEGG Ligand Database for Enzyme Nomenclature2.5.1.78
IUBMB Enzyme Nomenclature2.5.1.78
IntEnz2.5.1.78
MEDLINEFind literature relating to 2.5.1.78
MetaCyc2.5.1.78
Rhea expert-curated reactions2.5.1.78
UniProtKB/Swiss-Prot
Q9UVT8, RIB4_MAGO7Q9UUB1, RIB4_SCHPOP50861, RIB4_YEAST
Q89K80, RISB1_BRADUQ2YNC6, RISB1_BRUA2Q57DY1, RISB1_BRUAB
Q8YGH2, RISB1_BRUMEQ8G1E8, RISB1_BRUSUQ9A9S4, RISB1_CAUVC
Q889Q6, RISB1_PSESMQ983B0, RISB1_RHILOQ92QU0, RISB1_RHIME
P61726, RISB1_RHOPAQ89DI7, RISB2_BRADUQ2YKV1, RISB2_BRUA2
P61711, RISB2_BRUABP61712, RISB2_BRUMEP61713, RISB2_BRUSU
Q9A8J4, RISB2_CAUVCQ885J3, RISB2_PSESMQ986N2, RISB2_RHILO
Q92NI1, RISB2_RHIMEP61727, RISB2_RHOPAQ01994, RISBA_PHOLE
Q93E92, RISBB_PHOLEA3DBL9, RISB_ACET2Q6F6V3, RISB_ACIAD
B7GUW3, RISB_ACIB3B7I251, RISB_ACIB5B2I1Q0, RISB_ACIBC
B0VPU0, RISB_ACIBSA3MA34, RISB_ACIBTB0V9X5, RISB_ACIBY
A0LUD3, RISB_ACIC1B9MBL6, RISB_ACIETB7J444, RISB_ACIF2
B5ELV8, RISB_ACIF5A1W9I3, RISB_ACISJA3MZA3, RISB_ACTP2
B3H0P9, RISB_ACTP7B0BTN9, RISB_ACTPJP50856, RISB_ACTPL
A6VPE9, RISB_ACTSZQ9YC88, RISB_AERPEB6JGI3, RISB_AFIC5
C4Z8N0, RISB_AGARVQ8UG70, RISB_AGRFCQ21V18, RISB_ALBFT
A8EVW3, RISB_ALIB4Q5E6Z8, RISB_ALIF1B5FBF8, RISB_ALIFM
Q8G9G4, RISB_ALIFSB6EI99, RISB_ALISLQ5WH07, RISB_ALKCK
Q0ABQ4, RISB_ALKEHA6TM20, RISB_ALKMQB8JEW4, RISB_ANAD2
Q2ILH7, RISB_ANADEA7HDY3, RISB_ANADFB4UIM2, RISB_ANASK
B7GKI1, RISB_ANOFWO66529, RISB_AQUAEQ8GLK5, RISB_AQUPY
O80575, RISB_ARATHO28152, RISB_ARCFUQ5P3H3, RISB_AROAE
A0JVK2, RISB_ARTS2A8I0J5, RISB_AZOC5A1K280, RISB_AZOSB
C1DLH8, RISB_AZOVDC3P7P8, RISB_BACAAC3LIX8, RISB_BACAC
A0RIB4, RISB_BACAHQ44681, RISB_BACAMQ81MB5, RISB_BACAN
B7JLW7, RISB_BACC0P61719, RISB_BACC1B7IWM6, RISB_BACC2
C1EQY6, RISB_BACC3B7HAY5, RISB_BACC4B7HNM9, RISB_BACC7
B9IWX5, RISB_BACCQQ818X5, RISB_BACCRQ635G9, RISB_BACCZ
Q64XS0, RISB_BACFRQ6HE53, RISB_BACHKQ65HW7, RISB_BACLD
A9VG51, RISB_BACMKA8FER2, RISB_BACP2P11998, RISB_BACSU
Q89ZW8, RISB_BACTNA7Z674, RISB_BACVZA1USI4, RISB_BARBK
Q9REF4, RISB_BARHEQ6G005, RISB_BARQUA9IVC0, RISB_BART1
P61720, RISB_BDEBAB2ICH3, RISB_BEII9B7GN04, RISB_BIFLS
Q7VRI2, RISB_BLOFLQ494E6, RISB_BLOPBQ7WNT3, RISB_BORBR
Q7W143, RISB_BORPAA9I6G5, RISB_BORPDQ7VTN4, RISB_BORPE
C0QVI8, RISB_BRAHWB8D9N6, RISB_BUCA5Q9ZNM0, RISB_BUCAI
Q8K9A6, RISB_BUCAPB8D7Y8, RISB_BUCATQ89AB1, RISB_BUCBP
B1YUJ2, RISB_BURA4A0K5D2, RISB_BURCHB4EBT8, RISB_BURCJ
Q0BHJ7, RISB_BURCMA9AF24, RISB_BURM1A3MMR3, RISB_BURM7
A2S9D4, RISB_BURM9Q62HV4, RISB_BURMAA1V1K5, RISB_BURMS
B1JX76, RISB_BURO0Q1BYB6, RISB_BURO1A3NY88, RISB_BURP0
A3NCF9, RISB_BURP6Q63RP5, RISB_BURPSA4JC82, RISB_BURVG
B9MPC6, RISB_CALBDA4XHM5, RISB_CALS8A7ZBS6, RISB_CAMC1
A7GWZ6, RISB_CAMC5A0RQJ7, RISB_CAMFFA7HZG0, RISB_CAMHC
A8FKH0, RISB_CAMJ8A7H4Z4, RISB_CAMJDQ9PIB9, RISB_CAMJE
A1VYA3, RISB_CAMJJQ5HW84, RISB_CAMJRB9KFN9, RISB_CAMLR
Q3AC30, RISB_CARHZA9WFR1, RISB_CHLAAQ5L4Z3, RISB_CHLAB
Q3AUB5, RISB_CHLCHQ821P5, RISB_CHLCVQ255Z6, RISB_CHLFF
B3EHV0, RISB_CHLL2Q3B1F0, RISB_CHLL3Q9PLJ4, RISB_CHLMU
B3QL67, RISB_CHLP8B3EL33, RISB_CHLPBA1BJF9, RISB_CHLPD
A4SGN3, RISB_CHLPMQ9Z733, RISB_CHLPNB9LIH3, RISB_CHLSY
B0B8V8, RISB_CHLT2B3QWR1, RISB_CHLT3Q3KKW2, RISB_CHLTA
B0BAI7, RISB_CHLTBQ8KAW4, RISB_CHLTEO84737, RISB_CHLTR
A0LZH6, RISB_CHRFKQ7NVF3, RISB_CHRVOB5E854, RISB_CITBB
A8AK39, RISB_CITK8A5CPK0, RISB_CLAM3B0RC64, RISB_CLAMS
Q97LG8, RISB_CLOABA7FXC4, RISB_CLOB1C3L2U0, RISB_CLOB6
A6LSS9, RISB_CLOB8B2V4J4, RISB_CLOBAB2TJ82, RISB_CLOBB
A5I5U9, RISB_CLOBHC1FV67, RISB_CLOBJB1IL45, RISB_CLOBK
A7GH84, RISB_CLOBLB1KZ46, RISB_CLOBMB9E377, RISB_CLOK1
A5MZ82, RISB_CLOK5A0Q3H6, RISB_CLONNQ0TTN7, RISB_CLOP1
Q8XMW9, RISB_CLOPEQ0SVI9, RISB_CLOPSQ897Q7, RISB_CLOTE
Q485J2, RISB_COLP3C3PG33, RISB_CORA7O24753, RISB_CORAM
P61721, RISB_CORDIQ8FT58, RISB_COREFA4QEG8, RISB_CORGB
Q8NQ53, RISB_CORGLQ4JVI6, RISB_CORJKC4LIS3, RISB_CORK4
B1VDP6, RISB_CORU7B6J943, RISB_COXB1B6J134, RISB_COXB2
A9KC67, RISB_COXBNA9NCD4, RISB_COXBRQ83DP8, RISB_COXBU
B1WW99, RISB_CROS5A7MFG5, RISB_CROS8Q1LJV9, RISB_CUPMC
Q0K7T9, RISB_CUPNHQ474N4, RISB_CUPPJQ6A6Y6, RISB_CUTAK
Q11NR0, RISB_CYTH3Q3Z799, RISB_DEHM1A5FQE3, RISB_DEHMB
Q3ZY85, RISB_DEHMCC1CYL1, RISB_DEIDVQ1J1M8, RISB_DEIGD
Q9RXZ8, RISB_DEIRAC0QKW7, RISB_DESAHB8FJ77, RISB_DESAL
B1I2D4, RISB_DESAPB8J193, RISB_DESDAB8FXB6, RISB_DESHD
Q24WY8, RISB_DESHYA8ZTU7, RISB_DESOHQ6AP94, RISB_DESPS
A4J6A4, RISB_DESRMP61940, RISB_DESVHB8DJF2, RISB_DESVM
A1VEL0, RISB_DESVVA7ZIG8, RISB_ECO24B7UJN8, RISB_ECO27
B7MD73, RISB_ECO45B7L649, RISB_ECO55P61717, RISB_ECO57
B5Z3R9, RISB_ECO5EB7NJ82, RISB_ECO7IB7MQD0, RISB_ECO81
B7M3Q4, RISB_ECO8AC4ZTH2, RISB_ECOBWB1XF03, RISB_ECODH
A7ZX67, RISB_ECOHSQ0TKM6, RISB_ECOL5P61715, RISB_ECOL6
B1J034, RISB_ECOLCP61714, RISB_ECOLIB7N8W7, RISB_ECOLU
B6HZL6, RISB_ECOSEB1LJG5, RISB_ECOSMC5BCH5, RISB_EDWI9
B1H0H9, RISB_ENDTXA4W787, RISB_ENT38B2VHS9, RISB_ERWT9
Q2NAP7, RISB_ERYLHB7LMH2, RISB_ESCF3B1YEJ3, RISB_EXIS2
A5FNH3, RISB_FLAJ1A6H143, RISB_FLAPJQ2J850, RISB_FRACC
Q8RIR4, RISB_FUSNNC1A8F6, RISB_GEMATB9M1E6, RISB_GEODF
Q5KXK7, RISB_GEOKAQ39V66, RISB_GEOMGP61723, RISB_GEOSL
C6E3M5, RISB_GEOSMC5D3M9, RISB_GEOSWA4IQG7, RISB_GEOTN
A5G3J9, RISB_GEOURB8F5Z8, RISB_GLAP5Q7NLS9, RISB_GLOVI
Q7VM44, RISB_HAEDUQ4QKN2, RISB_HAEI8A5UCB8, RISB_HAEIE
A5UF15, RISB_HAEIGP45149, RISB_HAEINQ2S9R9, RISB_HAHCH
Q9KCL4, RISB_HALH5A1WVG1, RISB_HALHLB9LUV3, RISB_HALLT
B0R3T7, RISB_HALS3Q9HRM5, RISB_HALSAQ17Z25, RISB_HELAH
Q7VK54, RISB_HELHPB6JPA1, RISB_HELP2B5Z6D8, RISB_HELPG
Q1CVF3, RISB_HELPHQ9ZN56, RISB_HELPJB2UW06, RISB_HELPS
O24854, RISB_HELPYA9B4R4, RISB_HERA2Q0I3N6, RISB_HISS1
B0UU22, RISB_HISS2Q31FT1, RISB_HYDCUQ5QVF0, RISB_IDILO
Q28LT2, RISB_JANSCA6WCA2, RISB_KINRDB5Y0X6, RISB_KLEP3
A6T5E8, RISB_KLEP7B2GGU6, RISB_KOCRDC5CJ15, RISB_KOSOT
Q9CGU6, RISB_LACLAA2RLD8, RISB_LACLMQ88X16, RISB_LACPL
C1DB32, RISB_LARHHQ1MS15, RISB_LAWIPQ6AGR7, RISB_LEIXX
B0SB77, RISB_LEPBAQ04Q79, RISB_LEPBJQ054N5, RISB_LEPBL
B0ST02, RISB_LEPBPB1XYF6, RISB_LEPCPP61724, RISB_LEPIC
Q8F8T9, RISB_LEPINB1MYJ5, RISB_LEUCKQ03XY9, RISB_LEUMM
Q03PZ7, RISB_LEVBAA5VJX0, RISB_LIMRDB2G7B1, RISB_LIMRJ
B9E7J1, RISB_MACCJA0L3Z9, RISB_MAGMMQ2W4S6, RISB_MAGSA
Q65TX7, RISB_MANSMC6BYC7, RISB_MARSDA6UTD8, RISB_META3
Q8TPT7, RISB_METACQ46AS9, RISB_METBFB7KUS7, RISB_METC4
A9VYV8, RISB_METEPQ1H425, RISB_METFKQ57751, RISB_METJA
Q8TYL5, RISB_METKAA2SQG5, RISB_METLZA4G0E3, RISB_METM5
A9A8P1, RISB_METM6A6VI37, RISB_METM7Q8Q093, RISB_METMA
A3CRJ3, RISB_METMJP61730, RISB_METMPB8IPI3, RISB_METNO
B1ZJM3, RISB_METPBA2SK12, RISB_METPPB1LZB2, RISB_METRJ
A5UMS3, RISB_METS3B0UHS5, RISB_METS4A4YCS3, RISB_METS5
B8ENB9, RISB_METSBO27443, RISB_METTHA6UR43, RISB_METVS
B0JLM0, RISB_MICANC5CBJ8, RISB_MICLCQ2RK04, RISB_MOOTA
A0QI08, RISB_MYCA1B1MCA3, RISB_MYCA9P66035, RISB_MYCBO
A4TC12, RISB_MYCGIB8ZUN3, RISB_MYCLBQ9CCP3, RISB_MYCLE
B2HP68, RISB_MYCMMP61725, RISB_MYCPAA3PZ89, RISB_MYCSJ
A1UFM8, RISB_MYCSKQ1B9D5, RISB_MYCSSP9WHE8, RISB_MYCTO
P9WHE9, RISB_MYCTUA0PPL7, RISB_MYCUAA1T8K2, RISB_MYCVP
Q1D349, RISB_MYXXDB9L729, RISB_NAUPAQ5F9X9, RISB_NEIG1
B4RJT4, RISB_NEIG2A9M2W8, RISB_NEIM0P66036, RISB_NEIMA
P66037, RISB_NEIMBA1KSU7, RISB_NEIMFQ0AD61, RISB_NITEC
Q82S08, RISB_NITEUQ1QMB5, RISB_NITHXQ2YD51, RISB_NITMU
A6Q4R0, RISB_NITSBQ3SRV7, RISB_NITWNA1SJG9, RISB_NOCSJ
Q8YQ43, RISB_NOSS1Q2G669, RISB_NOVADQ8ELL1, RISB_OCEIH
Q30YL2, RISB_OLEA2A1R5R8, RISB_PAEATA1TPC1, RISB_PARC0
A6L8H3, RISB_PARD8Q7UA19, RISB_PARMWB2JED1, RISB_PARP8
B2T6D0, RISB_PARPJQ6MCT6, RISB_PARUWQ13V36, RISB_PARXL
P57869, RISB_PASMUQ6D848, RISB_PECASC6DB33, RISB_PECCP
Q03D86, RISB_PEDPAB4SGD1, RISB_PELPBA1ANJ6, RISB_PELPD
A5D1C7, RISB_PELTSC0QT44, RISB_PERMHQ7N0I9, RISB_PHOLL
P51963, RISB_PHOPOQ6LU12, RISB_PHOPRA6L3K7, RISB_PHOV8
Q6L153, RISB_PICTOA4SVH2, RISB_POLAQA1VRD9, RISB_POLNA
B1XTA7, RISB_POLNSQ129J1, RISB_POLSJB2RJ75, RISB_PORG3
Q7MUR5, RISB_PORGIB4S3W8, RISB_PROA2A3PFD1, RISB_PROM0
A2C5A7, RISB_PROM1A8G7E8, RISB_PROM2A2C5T7, RISB_PROM3
A9BD87, RISB_PROM4A2BZ29, RISB_PROM5Q317Z9, RISB_PROM9
Q7V9M7, RISB_PROMAB4EU19, RISB_PROMHQ7V977, RISB_PROMM
Q7UZL7, RISB_PROMPA2BTM4, RISB_PROMSQ46IE7, RISB_PROMT
Q15W98, RISB_PSEA6A6V049, RISB_PSEA7B7V7Q5, RISB_PSEA8
Q02SM0, RISB_PSEABQ9HWX5, RISB_PSEAEB8H6T9, RISB_PSECP
Q1IFM0, RISB_PSEE4A4XZ35, RISB_PSEMYA5VXW0, RISB_PSEP1
B0KL70, RISB_PSEPGQ88QH6, RISB_PSEPKQ3II28, RISB_PSET1
A1SUU5, RISB_PSYINQ8ZTE3, RISB_PYRAEA4WLK4, RISB_PYRAR
A3MX07, RISB_PYRCJQ8U4L8, RISB_PYRFUB1Y9N5, RISB_PYRNV
Q8Y1H8, RISB_RALN1B2U7F0, RISB_RALPJA9WR65, RISB_RENSM
A5V939, RISB_RHIWRQ7UGV1, RISB_RHOBAQ53107, RISB_RHOER
Q07MT5, RISB_RHOP5B8I3K7, RISB_RUMCHA1AWF3, RISB_RUTMC
Q21F19, RISB_SACD2A4FBK5, RISB_SACENQ980B5, RISB_SACS2
B5EXF8, RISB_SALA4A8LY39, RISB_SALAIQ57SE7, RISB_SALCH
B5FKS2, RISB_SALDCB5QTG5, RISB_SALEPB5R6R8, RISB_SALG2
B4T8Q8, RISB_SALHSB4SWQ9, RISB_SALNSQ5PFS8, RISB_SALPA
C0Q7U2, RISB_SALPCB5BDB5, RISB_SALPKQ2S3N1, RISB_SALRD
B4TM97, RISB_SALSVP66039, RISB_SALTIP66038, RISB_SALTY
A8GAN7, RISB_SERP5A1S4C0, RISB_SHEAMB8E6W6, RISB_SHEB2
A3D7C5, RISB_SHEB5A6WR47, RISB_SHEB8A9KYJ1, RISB_SHEB9
Q12Q43, RISB_SHEDOQ086C4, RISB_SHEFNB0TJZ0, RISB_SHEHH
A3QC62, RISB_SHELPQ8EBP3, RISB_SHEONA8H1Q5, RISB_SHEPA
A4Y961, RISB_SHEPCB8CJN2, RISB_SHEPWA8FSR4, RISB_SHESH
Q0HL88, RISB_SHESMQ0HXJ1, RISB_SHESRA1RHD5, RISB_SHESW
B1KJK4, RISB_SHEWMB2U4L8, RISB_SHIB3Q325I6, RISB_SHIBS
Q32JG9, RISB_SHIDSP61718, RISB_SHIFLQ3Z4Z4, RISB_SHISS
Q2NV98, RISB_SODGMC4XHY9, RISB_SOLM1Q01T71, RISB_SOLUE
Q1GNT5, RISB_SPHALQ9XH32, RISB_SPIOLA7X3K7, RISB_STAA1
A6U2N1, RISB_STAA2Q2FFX3, RISB_STAA3Q2FXG2, RISB_STAA8
A5ITT7, RISB_STAA9Q2YTM0, RISB_STAABQ5HF08, RISB_STAAC
A6QHU9, RISB_STAAEP61595, RISB_STAAMP99141, RISB_STAAN
Q6GFT6, RISB_STAARQ6G8G2, RISB_STAASA8Z4J3, RISB_STAAT
P0C600, RISB_STAAUP61597, RISB_STAAWB9DN29, RISB_STACT
Q5HNE4, RISB_STAEQQ8CNU3, RISB_STAESQ4L7B0, RISB_STAHJ
A3DLT5, RISB_STAMFQ49YJ6, RISB_STAS1Q3K1V6, RISB_STRA1
Q8E657, RISB_STRA3Q8E0I2, RISB_STRA5Q827L9, RISB_STRAW
Q9EWJ9, RISB_STRCOB1W4A5, RISB_STRGGB4SJC0, RISB_STRM5
B2FNL3, RISB_STRMKQ04MR3, RISB_STRP2B5E6C6, RISB_STRP4
C1CAI5, RISB_STRP7B1I8F3, RISB_STRPIB8ZKD0, RISB_STRPJ
P66040, RISB_STRPNB2IS11, RISB_STRPSP66041, RISB_STRR6
C1CBX9, RISB_STRZJC1CI69, RISB_STRZPC1CP44, RISB_STRZT
A4VHT4, RISB_STUS1Q4JAJ2, RISB_SULACQ30TJ8, RISB_SULDN
C3MZ62, RISB_SULIAC4KIE0, RISB_SULIKC3MR14, RISB_SULIL
C3MX02, RISB_SULIMC3NGF3, RISB_SULINC3N782, RISB_SULIY
O68250, RISB_SULMUA6QBK7, RISB_SULNBB2VAC3, RISB_SULSY
Q975M5, RISB_SULTOQ2LQN1, RISB_SYNASQ3A4L3, RISB_SYNC1
Q31KZ5, RISB_SYNE7A0LI20, RISB_SYNFMB1XLJ1, RISB_SYNP2
Q5N0X6, RISB_SYNP6A5GHU9, RISB_SYNPWA5GQ24, RISB_SYNR3
Q0IE03, RISB_SYNS3Q3B0Q0, RISB_SYNS9Q3ANH6, RISB_SYNSC
P73527, RISB_SYNY3C5BS85, RISB_TERTTQ47QZ8, RISB_THEFY
C5A697, RISB_THEGJQ5JD31, RISB_THEKOQ9X2E5, RISB_THEMA
B9K7K0, RISB_THENNB6YUQ8, RISB_THEONA5ILQ1, RISB_THEP1
B0KAI3, RISB_THEP3B0K0Z0, RISB_THEPXB1LAJ8, RISB_THESQ
P61728, RISB_THET2Q5SLF7, RISB_THET8Q8DMP4, RISB_THEVB
B5YHQ1, RISB_THEYDQ3SGU9, RISB_THIDAC4LAE1, RISB_TOLAT
B3E758, RISB_TRIL1Q3MCG0, RISB_TRIV2Q83HB9, RISB_TROW8
Q83FM6, RISB_TROWTA1WS77, RISB_VEREIA5CWS3, RISB_VESOH
A7MWU0, RISB_VIBC1Q9KPU4, RISB_VIBCHQ87RU4, RISB_VIBPA
Q8DF99, RISB_VIBVUQ7MN53, RISB_VIBVYQ8D291, RISB_WIGBR
P61729, RISB_WOLPMB3CL66, RISB_WOLPPQ7MAF0, RISB_WOLSU
Q5GT94, RISB_WOLTRC0R5L5, RISB_WOLWRQ8PPD6, RISB_XANAC
Q3BXI0, RISB_XANC5Q4UQU3, RISB_XANC8B0RVD2, RISB_XANCB
Q8PCM7, RISB_XANCPQ2NZ91, RISB_XANOMB2SNW4, RISB_XANOP
A7INA7, RISB_XANP2B2I8Q5, RISB_XYLF2Q9PES4, RISB_XYLFA
B0U4K3, RISB_XYLFMQ87AS7, RISB_XYLFTA1JNS3, RISB_YERE8
A7FLE8, RISB_YERP3Q1C4I4, RISB_YERPAB2K6T3, RISB_YERPB
Q8ZC41, RISB_YERPEA9R2J8, RISB_YERPGQ1CL92, RISB_YERPN
A4TPG7, RISB_YERPPQ66DV8, RISB_YERPSB1JIE2, RISB_YERPY
Q5NQA8, RISB_ZYMMO

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