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ENZYME

ENZYME entry: EC 2.5.1.78

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.78
Accepted Name
6,7-dimethyl-8-ribityllumazine synthase
Alternative Name(s)
lumazine synthase
Reaction catalysed
(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)
Comment(s)
Involved in riboflavin biosynthesis.
Cross-references
BRENDA2.5.1.78
EC2PDB2.5.1.78
ExplorEnz2.5.1.78
KEGG Ligand Database for Enzyme Nomenclature2.5.1.78
IUBMB Enzyme Nomenclature2.5.1.78
MEDLINEFind literature relating to 2.5.1.78
MetaCyc2.5.1.78
Rhea expert-curated reactions2.5.1.78
UniProtKB/Swiss-Prot
Q9UVT8, RIB4_PYRO7Q9UUB1, RIB4_SCHPOP50861, RIB4_YEAST
Q89K80, RISB1_BRADUQ2YNC6, RISB1_BRUA2Q57DY1, RISB1_BRUAB
Q8YGH2, RISB1_BRUMEQ8G1E8, RISB1_BRUSUQ9A9S4, RISB1_CAUVC
Q889Q6, RISB1_PSESMQ983B0, RISB1_RHILOQ92QU0, RISB1_RHIME
P61726, RISB1_RHOPAQ89DI7, RISB2_BRADUQ2YKV1, RISB2_BRUA2
P61711, RISB2_BRUABP61712, RISB2_BRUMEP61713, RISB2_BRUSU
Q9A8J4, RISB2_CAUVCQ885J3, RISB2_PSESMQ986N2, RISB2_RHILO
Q92NI1, RISB2_RHIMEP61727, RISB2_RHOPAQ01994, RISBA_PHOLE
Q93E92, RISBB_PHOLEA3DBL9, RISB_ACET2Q6F6V3, RISB_ACIAD
B7GUW3, RISB_ACIB3B7I251, RISB_ACIB5B2I1Q0, RISB_ACIBC
B0VPU0, RISB_ACIBSA3MA34, RISB_ACIBTB0V9X5, RISB_ACIBY
A0LUD3, RISB_ACIC1B9MBL6, RISB_ACIETB7J444, RISB_ACIF2
B5ELV8, RISB_ACIF5A1W9I3, RISB_ACISJA3MZA3, RISB_ACTP2
B3H0P9, RISB_ACTP7B0BTN9, RISB_ACTPJP50856, RISB_ACTPL
A6VPE9, RISB_ACTSZQ9YC88, RISB_AERPEB6JGI3, RISB_AFIC5
C4Z8N0, RISB_AGARVQ8UG70, RISB_AGRFCQ21V18, RISB_ALBFT
A8EVW3, RISB_ALIB4Q5E6Z8, RISB_ALIF1B5FBF8, RISB_ALIFM
Q8G9G4, RISB_ALIFSB6EI99, RISB_ALISLQ0ABQ4, RISB_ALKEH
A6TM20, RISB_ALKMQB8JEW4, RISB_ANAD2Q2ILH7, RISB_ANADE
A7HDY3, RISB_ANADFB4UIM2, RISB_ANASKB7GKI1, RISB_ANOFW
O66529, RISB_AQUAEQ8GLK5, RISB_AQUPYO80575, RISB_ARATH
O28152, RISB_ARCFUQ5P3H3, RISB_AROAEA0JVK2, RISB_ARTS2
A8I0J5, RISB_AZOC5A1K280, RISB_AZOSBC1DLH8, RISB_AZOVD
C3P7P8, RISB_BACAAC3LIX8, RISB_BACACA0RIB4, RISB_BACAH
Q44681, RISB_BACAMQ81MB5, RISB_BACANB7JLW7, RISB_BACC0
P61719, RISB_BACC1B7IWM6, RISB_BACC2C1EQY6, RISB_BACC3
B7HAY5, RISB_BACC4B7HNM9, RISB_BACC7B9IWX5, RISB_BACCQ
Q818X5, RISB_BACCRQ635G9, RISB_BACCZQ64XS0, RISB_BACFR
Q6HE53, RISB_BACHKQ65HW7, RISB_BACLDA9VG51, RISB_BACMK
A8FER2, RISB_BACP2P11998, RISB_BACSUQ89ZW8, RISB_BACTN
A7Z674, RISB_BACVZA1USI4, RISB_BARBKQ9REF4, RISB_BARHE
Q6G005, RISB_BARQUA9IVC0, RISB_BART1P61720, RISB_BDEBA
B2ICH3, RISB_BEII9B7GN04, RISB_BIFLSQ7VRI2, RISB_BLOFL
Q494E6, RISB_BLOPBQ7WNT3, RISB_BORBRQ7W143, RISB_BORPA
A9I6G5, RISB_BORPDQ7VTN4, RISB_BORPEC0QVI8, RISB_BRAHW
B8D9N6, RISB_BUCA5Q9ZNM0, RISB_BUCAIQ8K9A6, RISB_BUCAP
B8D7Y8, RISB_BUCATQ89AB1, RISB_BUCBPB1YUJ2, RISB_BURA4
A0K5D2, RISB_BURCHB4EBT8, RISB_BURCJQ0BHJ7, RISB_BURCM
A9AF24, RISB_BURM1A3MMR3, RISB_BURM7A2S9D4, RISB_BURM9
Q62HV4, RISB_BURMAA1V1K5, RISB_BURMSB1JX76, RISB_BURO0
Q1BYB6, RISB_BURO1A3NY88, RISB_BURP0A3NCF9, RISB_BURP6
Q63RP5, RISB_BURPSA4JC82, RISB_BURVGB9MPC6, RISB_CALBD
A4XHM5, RISB_CALS8A7ZBS6, RISB_CAMC1A7GWZ6, RISB_CAMC5
A0RQJ7, RISB_CAMFFA7HZG0, RISB_CAMHCA8FKH0, RISB_CAMJ8
A7H4Z4, RISB_CAMJDQ9PIB9, RISB_CAMJEA1VYA3, RISB_CAMJJ
Q5HW84, RISB_CAMJRB9KFN9, RISB_CAMLRQ3AC30, RISB_CARHZ
A9WFR1, RISB_CHLAAQ5L4Z3, RISB_CHLABQ3AUB5, RISB_CHLCH
Q821P5, RISB_CHLCVQ255Z6, RISB_CHLFFB3EHV0, RISB_CHLL2
Q3B1F0, RISB_CHLL3Q9PLJ4, RISB_CHLMUB3QL67, RISB_CHLP8
B3EL33, RISB_CHLPBA1BJF9, RISB_CHLPDA4SGN3, RISB_CHLPM
Q9Z733, RISB_CHLPNB9LIH3, RISB_CHLSYB0B8V8, RISB_CHLT2
B3QWR1, RISB_CHLT3Q3KKW2, RISB_CHLTAB0BAI7, RISB_CHLTB
Q8KAW4, RISB_CHLTEO84737, RISB_CHLTRA0LZH6, RISB_CHRFK
Q7NVF3, RISB_CHRVOB5E854, RISB_CITBBA8AK39, RISB_CITK8
A5CPK0, RISB_CLAM3B0RC64, RISB_CLASEQ97LG8, RISB_CLOAB
A7FXC4, RISB_CLOB1C3L2U0, RISB_CLOB6A6LSS9, RISB_CLOB8
B2V4J4, RISB_CLOBAB2TJ82, RISB_CLOBBA5I5U9, RISB_CLOBH
C1FV67, RISB_CLOBJB1IL45, RISB_CLOBKA7GH84, RISB_CLOBL
B1KZ46, RISB_CLOBMB9E377, RISB_CLOK1A5MZ82, RISB_CLOK5
A0Q3H6, RISB_CLONNQ0TTN7, RISB_CLOP1Q8XMW9, RISB_CLOPE
Q0SVI9, RISB_CLOPSQ897Q7, RISB_CLOTEQ485J2, RISB_COLP3
C3PG33, RISB_CORA7O24753, RISB_CORAMP61721, RISB_CORDI
Q8FT58, RISB_COREFA4QEG8, RISB_CORGBQ8NQ53, RISB_CORGL
Q4JVI6, RISB_CORJKC4LIS3, RISB_CORK4B1VDP6, RISB_CORU7
B6J943, RISB_COXB1B6J134, RISB_COXB2A9KC67, RISB_COXBN
A9NCD4, RISB_COXBRQ83DP8, RISB_COXBUB1WW99, RISB_CROS5
A7MFG5, RISB_CROS8Q1LJV9, RISB_CUPMCQ0K7T9, RISB_CUPNH
Q474N4, RISB_CUPPJQ6A6Y6, RISB_CUTAKQ11NR0, RISB_CYTH3
Q3Z799, RISB_DEHM1A5FQE3, RISB_DEHMBQ3ZY85, RISB_DEHMC
C1CYL1, RISB_DEIDVQ1J1M8, RISB_DEIGDQ9RXZ8, RISB_DEIRA
C0QKW7, RISB_DESAHB8FJ77, RISB_DESALB1I2D4, RISB_DESAP
B8J193, RISB_DESDAB8FXB6, RISB_DESHDQ24WY8, RISB_DESHY
A8ZTU7, RISB_DESOHQ6AP94, RISB_DESPSA4J6A4, RISB_DESRM
A7ZIG8, RISB_ECO24B7UJN8, RISB_ECO27B7MD73, RISB_ECO45
B7L649, RISB_ECO55P61717, RISB_ECO57B5Z3R9, RISB_ECO5E
B7NJ82, RISB_ECO7IB7MQD0, RISB_ECO81B7M3Q4, RISB_ECO8A
C4ZTH2, RISB_ECOBWB1XF03, RISB_ECODHA7ZX67, RISB_ECOHS
Q0TKM6, RISB_ECOL5P61715, RISB_ECOL6B1J034, RISB_ECOLC
P61714, RISB_ECOLIB7N8W7, RISB_ECOLUB6HZL6, RISB_ECOSE
B1LJG5, RISB_ECOSMA4XZ35, RISB_ECTM1C5BCH5, RISB_EDWI9
B1H0H9, RISB_ENDTXA4W787, RISB_ENT38B2VHS9, RISB_ERWT9
Q2NAP7, RISB_ERYLHB7LMH2, RISB_ESCF3B1YEJ3, RISB_EXIS2
A5FNH3, RISB_FLAJ1A6H143, RISB_FLAPJQ2J850, RISB_FRACC
Q8RIR4, RISB_FUSNNC1A8F6, RISB_GEMATB9M1E6, RISB_GEODF
Q5KXK7, RISB_GEOKAQ39V66, RISB_GEOMGP61723, RISB_GEOSL
C6E3M5, RISB_GEOSMC5D3M9, RISB_GEOSWA4IQG7, RISB_GEOTN
A5G3J9, RISB_GEOURB8F5Z8, RISB_GLAP5Q7NLS9, RISB_GLOVI
Q7VM44, RISB_HAEDUQ4QKN2, RISB_HAEI8A5UCB8, RISB_HAEIE
A5UF15, RISB_HAEIGP45149, RISB_HAEINQ2S9R9, RISB_HAHCH
Q9KCL4, RISB_HALH5A1WVG1, RISB_HALHLB9LUV3, RISB_HALLT
B0R3T7, RISB_HALS3Q9HRM5, RISB_HALSAQ17Z25, RISB_HELAH
Q7VK54, RISB_HELHPB6JPA1, RISB_HELP2B5Z6D8, RISB_HELPG
Q1CVF3, RISB_HELPHQ9ZN56, RISB_HELPJB2UW06, RISB_HELPS
O24854, RISB_HELPYA9B4R4, RISB_HERA2Q0I3N6, RISB_HISS1
B0UU22, RISB_HISS2Q31FT1, RISB_HYDCUQ5QVF0, RISB_IDILO
Q28LT2, RISB_JANSCA6WCA2, RISB_KINRDA6T5E8, RISB_KLEP7
B5Y0X6, RISB_KLEV3B2GGU6, RISB_KOCRDC5CJ15, RISB_KOSOT
Q9CGU6, RISB_LACLAA2RLD8, RISB_LACLMQ88X16, RISB_LACPL
C1DB32, RISB_LARHHQ1MS15, RISB_LAWIPQ6AGR7, RISB_LEIXX
B0SB77, RISB_LEPBAQ04Q79, RISB_LEPBJQ054N5, RISB_LEPBL
B0ST02, RISB_LEPBPB1XYF6, RISB_LEPCPP61724, RISB_LEPIC
Q8F8T9, RISB_LEPINB1MYJ5, RISB_LEUCKQ03XY9, RISB_LEUMM
Q03PZ7, RISB_LEVBAA5VJX0, RISB_LIMRDB2G7B1, RISB_LIMRJ
B9E7J1, RISB_MACCJA0L3Z9, RISB_MAGMMQ65TX7, RISB_MANSM
C6BYC7, RISB_MARSDA6UTD8, RISB_META3Q8TPT7, RISB_METAC
Q46AS9, RISB_METBFB7KUS7, RISB_METC4A9VYV8, RISB_METEP
Q1H425, RISB_METFKQ57751, RISB_METJAQ8TYL5, RISB_METKA
A2SQG5, RISB_METLZA4G0E3, RISB_METM5A9A8P1, RISB_METM6
A6VI37, RISB_METM7Q8Q093, RISB_METMAA3CRJ3, RISB_METMJ
P61730, RISB_METMPB8IPI3, RISB_METNOB1ZJM3, RISB_METPB
A2SK12, RISB_METPPB1LZB2, RISB_METRJA5UMS3, RISB_METS3
B0UHS5, RISB_METS4A4YCS3, RISB_METS5B8ENB9, RISB_METSB
O27443, RISB_METTHA6UR43, RISB_METVSB0JLM0, RISB_MICAN
C5CBJ8, RISB_MICLCQ2RK04, RISB_MOOTAA0QI08, RISB_MYCA1
B1MCA3, RISB_MYCA9P66035, RISB_MYCBOA4TC12, RISB_MYCGI
B8ZUN3, RISB_MYCLBQ9CCP3, RISB_MYCLEB2HP68, RISB_MYCMM
P61725, RISB_MYCPAA3PZ89, RISB_MYCSJA1UFM8, RISB_MYCSK
Q1B9D5, RISB_MYCSSP9WHE8, RISB_MYCTOP9WHE9, RISB_MYCTU
A0PPL7, RISB_MYCUAA1T8K2, RISB_MYCVPQ1D349, RISB_MYXXD
B9L729, RISB_NAUPAQ5F9X9, RISB_NEIG1B4RJT4, RISB_NEIG2
A9M2W8, RISB_NEIM0P66036, RISB_NEIMAP66037, RISB_NEIMB
A1KSU7, RISB_NEIMFQ0AD61, RISB_NITECQ82S08, RISB_NITEU
Q1QMB5, RISB_NITHXQ2YD51, RISB_NITMUA6Q4R0, RISB_NITSB
P61940, RISB_NITV2A1VEL0, RISB_NITV4B8DJF2, RISB_NITV9
Q3SRV7, RISB_NITWNA1SJG9, RISB_NOCSJQ8YQ43, RISB_NOSS1
Q2G669, RISB_NOVADQ8ELL1, RISB_OCEIHQ30YL2, RISB_OLEA2
A1R5R8, RISB_PAEATA1TPC1, RISB_PARC0A6L8H3, RISB_PARD8
Q2W4S6, RISB_PARM1Q7UA19, RISB_PARMWB2JED1, RISB_PARP8
B2T6D0, RISB_PARPJQ6MCT6, RISB_PARUWQ13V36, RISB_PARXL
P57869, RISB_PASMUQ6D848, RISB_PECASC6DB33, RISB_PECCP
Q03D86, RISB_PEDPAB4SGD1, RISB_PELPBA1ANJ6, RISB_PELPD
A5D1C7, RISB_PELTSC0QT44, RISB_PERMHQ7N0I9, RISB_PHOLL
P51963, RISB_PHOPOQ6LU12, RISB_PHOPRA6L3K7, RISB_PHOV8
B1XLJ1, RISB_PICP2Q6L153, RISB_PICTOA4SVH2, RISB_POLAQ
A1VRD9, RISB_POLNAB1XTA7, RISB_POLNSQ129J1, RISB_POLSJ
B2RJ75, RISB_PORG3Q7MUR5, RISB_PORGIB4S3W8, RISB_PROA2
A3PFD1, RISB_PROM0A2C5A7, RISB_PROM1A8G7E8, RISB_PROM2
A2C5T7, RISB_PROM3A9BD87, RISB_PROM4A2BZ29, RISB_PROM5
Q317Z9, RISB_PROM9Q7V9M7, RISB_PROMAB4EU19, RISB_PROMH
Q7V977, RISB_PROMMQ7UZL7, RISB_PROMPA2BTM4, RISB_PROMS
Q46IE7, RISB_PROMTQ15W98, RISB_PSEA6B7V7Q5, RISB_PSEA8
Q02SM0, RISB_PSEABQ9HWX5, RISB_PSEAEB8H6T9, RISB_PSECP
Q1IFM0, RISB_PSEE4A5VXW0, RISB_PSEP1A6V049, RISB_PSEP7
B0KL70, RISB_PSEPGQ88QH6, RISB_PSEPKQ3II28, RISB_PSET1
A1SUU5, RISB_PSYINQ8ZTE3, RISB_PYRAEA4WLK4, RISB_PYRAR
A3MX07, RISB_PYRCJQ8U4L8, RISB_PYRFUB1Y9N5, RISB_PYRNV
Q8Y1H8, RISB_RALN1B2U7F0, RISB_RALPJA9WR65, RISB_RENSM
A5V939, RISB_RHIWRQ7UGV1, RISB_RHOBAQ53107, RISB_RHOER
Q07MT5, RISB_RHOP5B8I3K7, RISB_RUMCHA1AWF3, RISB_RUTMC
Q21F19, RISB_SACD2A4FBK5, RISB_SACENC3NGF3, RISB_SACI1
C3MR14, RISB_SACI2C3MZ62, RISB_SACI3C3MX02, RISB_SACI4
C4KIE0, RISB_SACI6C3N782, RISB_SACI7Q980B5, RISB_SACS2
B5EXF8, RISB_SALA4A8LY39, RISB_SALAIQ57SE7, RISB_SALCH
B5FKS2, RISB_SALDCB5QTG5, RISB_SALEPB5R6R8, RISB_SALG2
B4T8Q8, RISB_SALHSB4SWQ9, RISB_SALNSQ5PFS8, RISB_SALPA
C0Q7U2, RISB_SALPCB5BDB5, RISB_SALPKQ2S3N1, RISB_SALRD
B4TM97, RISB_SALSVP66039, RISB_SALTIP66038, RISB_SALTY
A8GAN7, RISB_SERP5A1S4C0, RISB_SHEAMB8E6W6, RISB_SHEB2
A3D7C5, RISB_SHEB5A6WR47, RISB_SHEB8A9KYJ1, RISB_SHEB9
Q12Q43, RISB_SHEDOQ086C4, RISB_SHEFNB0TJZ0, RISB_SHEHH
A3QC62, RISB_SHELPQ8EBP3, RISB_SHEONA8H1Q5, RISB_SHEPA
A4Y961, RISB_SHEPCB8CJN2, RISB_SHEPWA8FSR4, RISB_SHESH
Q0HL88, RISB_SHESMQ0HXJ1, RISB_SHESRA1RHD5, RISB_SHESW
B1KJK4, RISB_SHEWMB2U4L8, RISB_SHIB3Q325I6, RISB_SHIBS
Q32JG9, RISB_SHIDSP61718, RISB_SHIFLQ3Z4Z4, RISB_SHISS
Q5WH07, RISB_SHOC1Q2NV98, RISB_SODGMC4XHY9, RISB_SOLM1
Q01T71, RISB_SOLUEQ1GNT5, RISB_SPHALQ9XH32, RISB_SPIOL
A7X3K7, RISB_STAA1A6U2N1, RISB_STAA2Q2FFX3, RISB_STAA3
Q2FXG2, RISB_STAA8A5ITT7, RISB_STAA9Q2YTM0, RISB_STAAB
Q5HF08, RISB_STAACA6QHU9, RISB_STAAEP61595, RISB_STAAM
P99141, RISB_STAANQ6GFT6, RISB_STAARQ6G8G2, RISB_STAAS
A8Z4J3, RISB_STAATP0C600, RISB_STAAUP61597, RISB_STAAW
B9DN29, RISB_STACTQ5HNE4, RISB_STAEQQ8CNU3, RISB_STAES
Q4L7B0, RISB_STAHJA3DLT5, RISB_STAMFQ49YJ6, RISB_STAS1
Q3K1V6, RISB_STRA1Q8E657, RISB_STRA3Q8E0I2, RISB_STRA5
Q827L9, RISB_STRAWQ9EWJ9, RISB_STRCOB1W4A5, RISB_STRGG
B4SJC0, RISB_STRM5B2FNL3, RISB_STRMKQ04MR3, RISB_STRP2
B5E6C6, RISB_STRP4C1CAI5, RISB_STRP7B1I8F3, RISB_STRPI
B8ZKD0, RISB_STRPJP66040, RISB_STRPNB2IS11, RISB_STRPS
P66041, RISB_STRR6C1CBX9, RISB_STRZJC1CI69, RISB_STRZP
C1CP44, RISB_STRZTA4VHT4, RISB_STUS1Q4JAJ2, RISB_SULAC
Q30TJ8, RISB_SULDNO68250, RISB_SULMUA6QBK7, RISB_SULNB
B2VAC3, RISB_SULSYQ975M5, RISB_SULTOQ2LQN1, RISB_SYNAS
Q3A4L3, RISB_SYNC1Q31KZ5, RISB_SYNE7A0LI20, RISB_SYNFM
Q5N0X6, RISB_SYNP6A5GHU9, RISB_SYNPWA5GQ24, RISB_SYNR3
Q0IE03, RISB_SYNS3Q3B0Q0, RISB_SYNS9Q3ANH6, RISB_SYNSC
P73527, RISB_SYNY3C5BS85, RISB_TERTTQ47QZ8, RISB_THEFY
C5A697, RISB_THEGJQ5JD31, RISB_THEKOQ9X2E5, RISB_THEMA
B9K7K0, RISB_THENNB6YUQ8, RISB_THEONA5ILQ1, RISB_THEP1
B0KAI3, RISB_THEP3B0K0Z0, RISB_THEPXB1LAJ8, RISB_THESQ
P61728, RISB_THET2Q5SLF7, RISB_THET8Q8DMP4, RISB_THEVB
B5YHQ1, RISB_THEYDQ3SGU9, RISB_THIDAC4LAE1, RISB_TOLAT
B3E758, RISB_TRIL1Q3MCG0, RISB_TRIV2Q83HB9, RISB_TROW8
Q83FM6, RISB_TROWTA1WS77, RISB_VEREIA5CWS3, RISB_VESOH
A7MWU0, RISB_VIBC1Q9KPU4, RISB_VIBCHQ87RU4, RISB_VIBPA
Q8DF99, RISB_VIBVUQ7MN53, RISB_VIBVYQ8D291, RISB_WIGBR
P61729, RISB_WOLPMB3CL66, RISB_WOLPPQ7MAF0, RISB_WOLSU
Q5GT94, RISB_WOLTRC0R5L5, RISB_WOLWRQ8PPD6, RISB_XANAC
Q4UQU3, RISB_XANC8B0RVD2, RISB_XANCBQ8PCM7, RISB_XANCP
Q3BXI0, RISB_XANE5Q2NZ91, RISB_XANOMB2SNW4, RISB_XANOP
A7INA7, RISB_XANP2B2I8Q5, RISB_XYLF2Q9PES4, RISB_XYLFA
B0U4K3, RISB_XYLFMQ87AS7, RISB_XYLFTA1JNS3, RISB_YERE8
A7FLE8, RISB_YERP3Q1C4I4, RISB_YERPAB2K6T3, RISB_YERPB
Q8ZC41, RISB_YERPEA9R2J8, RISB_YERPGQ1CL92, RISB_YERPN
A4TPG7, RISB_YERPPQ66DV8, RISB_YERPSB1JIE2, RISB_YERPY
Q5NQA8, RISB_ZYMMO

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