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ENZYME

ENZYME entry: EC 2.5.1.85

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.85
Accepted Name
all-trans-nonaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific]
Alternative Name(s)
nonaprenyl diphosphate synthase
solanesyl diphosphate synthase
Reaction catalysed
5 isopentenyl diphosphate + (2E,6E,10E)-geranylgeranyl diphosphate = all-trans-nonaprenyl diphosphate + 5 diphosphate
Comment(s)
  • Geranylgeranyl diphosphate is preferred over farnesyl diphosphate as allylic substrate.
  • The plant Arabidopsis thaliana has two different enzymes that catalyze this reaction.
  • SPS1 contributes to the biosynthesis of the ubiquinone side-chain while SPS2 supplies the precursor of the plastoquinone side-chains.
  • Formerly EC 2.5.1.11.
Cross-references
BRENDA2.5.1.85
EC2PDB2.5.1.85
ExplorEnz2.5.1.85
KEGG Ligand Database for Enzyme Nomenclature2.5.1.85
IUBMB Enzyme Nomenclature2.5.1.85
MEDLINEFind literature relating to 2.5.1.85
MetaCyc2.5.1.85
Rhea expert-curated reactions2.5.1.85
UniProtKB/Swiss-Prot
O06428, NPPPS_MYCTUQ8S948, SPS1_ARATHQ76FS5, SPS2_ARATH
Q5HZ00, SPS3_ARATH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-