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ENZYME entry: EC 2.5.1.89

Accepted Name
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl- diphosphate specific).
Reaction catalysed
Geranylgeranyl diphosphate + 7 isopentenyl diphosphate <=> 7 diphosphate + tritrans,heptacis-undecaprenyl diphosphate
Comment(s)
  • This enzyme is involved in the biosynthesis of the glycosyl carrier lipid in some archaebacteria.
  • Unlike EC 2.5.1.31, its counterpart in most bacteria, it prefers geranylgeranyl diphosphate to farnesyl diphosphate as the allylic substrate, resulting in production of a tritrans,polycis variant of undecaprenyl diphosphate.
Cross-references
BRENDA2.5.1.89
EC2PDB2.5.1.89
ExplorEnz2.5.1.89
PRIAM enzyme-specific profiles2.5.1.89
KEGG Ligand Database for Enzyme Nomenclature2.5.1.89
IUBMB Enzyme Nomenclature2.5.1.89
IntEnz2.5.1.89
MEDLINEFind literature relating to 2.5.1.89
MetaCyc2.5.1.89
Rhea expert-curated reactions2.5.1.89
UniProtKB/Swiss-Prot
Q9YC66, UPPS_AERPE;  O29049, UPPS_ARCFU;  Q5V1I1, UPPS_HALMA;  
Q9HP68, UPPS_HALSA;  Q8TJQ7, UPPS_METAC;  Q58767, UPPS_METJA;  
Q8TXA7, UPPS_METKA;  Q8PZ76, UPPS_METMA;  O26334, UPPS_METTH;  
Q6KZ89, UPPS_PICTO;  Q9V157, UPPS_PYRAB;  Q8ZU54, UPPS_PYRAE;  
Q8U0I8, UPPS_PYRFU;  O59258, UPPS_PYRHO;  Q980W4, UPPS_SACS2;  
Q9HH76, UPPS_SULAC;  Q976K2, UPPS_SULTO;  Q9HKQ0, UPPS_THEAC;  
Q5JGE1, UPPS_THEKO;  Q97B58, UPPS_THEVO;  

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