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ENZYME

ENZYME entry: EC 2.5.1.90

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.90
Accepted Name
all-trans-octaprenyl-diphosphate synthase
Alternative Name(s)
octaprenyl pyrophosphate synthetase
terpenyl pyrophosphate synthetase
trans-heptaprenyltranstransferase
trans-prenyltransferase
Reaction catalysed
5 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-octaprenyl diphosphate + 5 diphosphate
Comment(s)
  • This enzyme catalyzes the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate, the isoprenoid side chain of ubiquinone-8 and menaquinone-8.
  • The enzyme adds five isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry.
Cross-references
BRENDA2.5.1.90
EC2PDB2.5.1.90
ExplorEnz2.5.1.90
KEGG Ligand Database for Enzyme Nomenclature2.5.1.90
IUBMB Enzyme Nomenclature2.5.1.90
MEDLINEFind literature relating to 2.5.1.90
MetaCyc2.5.1.90
Rhea expert-curated reactions2.5.1.90
UniProtKB/Swiss-Prot
P0AD57, ISPB_ECOLIP44916, ISPB_HAEINP0AD58, ISPB_SHIFL

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-