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ENZYME entry: EC 2.6.1.1

Accepted Name
Aspartate transaminase.
Alternative Name(s)
Aspartate aminotransferase.
Glutamic--aspartic transaminase.
Glutamic--oxaloacetic transaminase.
Transaminase A.
Reaction catalysed
L-aspartate + 2-oxoglutarate <=> oxaloacetate + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.
  • This activity can be formed from EC 2.6.1.57 by controlled proteolysis.
Cross-references
PROSITEPDOC00098
BRENDA2.6.1.1
EC2PDB2.6.1.1
ExplorEnz2.6.1.1
PRIAM enzyme-specific profiles2.6.1.1
KEGG Ligand Database for Enzyme Nomenclature2.6.1.1
IUBMB Enzyme Nomenclature2.6.1.1
IntEnz2.6.1.1
MEDLINEFind literature relating to 2.6.1.1
MetaCyc2.6.1.1
UniProtKB/Swiss-Prot
O67781, AAPAT_AQUAE;  Q8KDS8, AAPAT_CHLTE;  Q82WA8, AAPAT_NITEU;  
O86459, AAPAT_RHILP;  Q02635, AAPAT_RHIME;  A3PMF8, AAPAT_RHOS1;  
Q1RGV0, AAPAT_RICBR;  Q92JE7, AAPAT_RICCN;  Q4UND3, AAPAT_RICFE;  
Q9ZE56, AAPAT_RICPR;  Q68XV9, AAPAT_RICTY;  O33822, AAPAT_THEAQ;  
Q56232, AAPAT_THET8;  P46643, AAT1_ARATH;  P53001, AAT1_BACSU;  
P28011, AAT1_MEDSA;  P85906, AAT1_PSEMZ;  P46645, AAT2_ARATH;  
P85951, AAT2_PSEMZ;  P46644, AAT3_ARATH;  O07587, AAT3_BACSU;  
P46646, AAT4_ARATH;  P46248, AAT5_ARATH;  Q2T9S8, AATC2_BOVIN;  
Q8NHS2, AATC2_HUMAN;  Q7TSV6, AATC2_MOUSE;  P33097, AATC_BOVIN;  
Q22067, AATC_CAEEL;  P00504, AATC_CHICK;  P28734, AATC_DAUCA;  
Q54SF7, AATC_DICDI;  P08906, AATC_HORSE;  P17174, AATC_HUMAN;  
Q4R5L1, AATC_MACFA;  P05201, AATC_MOUSE;  P37833, AATC_ORYSJ;  
A5A6K8, AATC_PANTR;  P00503, AATC_PIG;  Q5R691, AATC_PONAB;  
P12343, AATC_RABIT;  P13221, AATC_RAT;  O42652, AATC_SCHPO;  
P23542, AATC_YEAST;  P12344, AATM_BOVIN;  P85310, AATM_CATRO;  
P00508, AATM_CHICK;  Q55F21, AATM_DICDI;  P08907, AATM_HORSE;  
P00505, AATM_HUMAN;  P26563, AATM_LUPAN;  Q4R559, AATM_MACFA;  
P05202, AATM_MOUSE;  P00506, AATM_PIG;  Q5REB0, AATM_PONAB;  
P12345, AATM_RABIT;  P00507, AATM_RAT;  O94320, AATM_SCHPO;  
Q28F67, AATM_XENTR;  Q01802, AATM_YEAST;  P23034, AAT_BACY2;  
C6C2Z3, AAT_DICP7;  P00509, AAT_ECOLI;  Q59228, AAT_GEOSE;  
P44425, AAT_HAEIN;  P52069, AAT_METEX;  Q60317, AAT_METJA;  
P63499, AAT_MYCBO;  P9WQ90, AAT_MYCTO;  P9WQ91, AAT_MYCTU;  
P72173, AAT_PSEAE;  Q9V0L2, AAT_PYRAB;  O58489, AAT_PYRHO;  
P58350, AAT_RHIME;  Q06191, AAT_RHIML;  P14909, AAT_SACS2;  
Q56114, AAT_SALTI;  P58661, AAT_SALTY;  Q82DR2, AAT_STRAW;  
P36692, AAT_STRGR;  Q60013, AAT_STRVG;  Q4J8X2, AAT_SULAC;  
Q972A2, AAT_SULTO;  Q55128, AAT_SYNY3;  O93744, AAT_THEKO;  
Q9X0Y2, AAT_THEMA;  Q93QX0, ASDA_COMTE;  Q53IZ1, ASDP_PSESP;  
Q9SIE1, PAT_ARATH;  E9L7A5, PAT_PETHY;  Q5F4K8, PAT_PINPS;  
O85746, TYRB_KLEPN;  

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