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ENZYME entry: EC 2.6.1.102

Accepted Name
GDP-perosamine synthase.
Alternative Name(s)
GDP-4-keto-6-deoxy-D-mannose-4-aminotransferase.
Reaction catalysed
GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate <=> GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • D-perosamine is one of several dideoxy sugars found in the O-specific polysaccharide of the lipopolysaccharide component of the outer membrane of Gram-negative bacteria.
  • The enzyme catalyzes the final step in GDP-perosamine synthesis.
Cross-references
BRENDA2.6.1.102
EC2PDB2.6.1.102
ExplorEnz2.6.1.102
PRIAM enzyme-specific profiles2.6.1.102
KEGG Ligand Database for Enzyme Nomenclature2.6.1.102
IUBMB Enzyme Nomenclature2.6.1.102
IntEnz2.6.1.102
MEDLINEFind literature relating to 2.6.1.102
MetaCyc2.6.1.102
UniProtKB/Swiss-Prot
Q9A9H3, GDPPS_CAUVC;  Q7DBF3, GDPPS_ECO57;  Q06953, GDPPS_VIBCL;  

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