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ENZYME entry: EC 2.6.1.105

Accepted Name
lysine--8-amino-7-oxononanoate transaminase.
Alternative Name(s)
DAPA aminotransferase.
Reaction catalysed
(8S)-8-amino-7-oxononanoate + L-lysine <=> (7R,8S)-7,8-diammoniononanoate + (S)-2-amino-6-oxohexanoate
Comment(s)
  • Participates in the pathway for biotin biosynthesis.
  • The enzyme from the bacterium Bacillus subtilis cannot use S-adenosyl-L-methionine as amino donor and catalyzes an alternative reaction for the conversion of 8-amino-7-oxononanoate to 7,8- diaminononanoate (cf. EC 2.6.1.62).
  • Formerly EC 2.6.1.n2.
Cross-references
BRENDA2.6.1.105
EC2PDB2.6.1.105
ExplorEnz2.6.1.105
PRIAM enzyme-specific profiles2.6.1.105
KEGG Ligand Database for Enzyme Nomenclature2.6.1.105
IUBMB Enzyme Nomenclature2.6.1.105
IntEnz2.6.1.105
MEDLINEFind literature relating to 2.6.1.105
MetaCyc2.6.1.105
Rhea expert-curated reactions2.6.1.105
UniProtKB/Swiss-Prot
P53555, BIOK_BACSU

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