ENZYME entry: EC 2.6.1.106
Accepted Name |
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase.
|
Reaction catalysed |
2-oxoglutarate + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose <=> dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose + L-glutamate |
Comment(s) |
- The enzyme is involved in the biosynthesis of dTDP-alpha-D-
desosamine, a sugar found in several bacterial macrolide antibiotics
including erythromycin, megalomicin A, mycinamicin II,
and oleandomycin.
- The reaction occurs in the reverse direction.
|
Cross-references |
BRENDA | 2.6.1.106 |
EC2PDB | 2.6.1.106 |
ExplorEnz | 2.6.1.106 |
PRIAM enzyme-specific profiles | 2.6.1.106 |
KEGG Ligand Database for Enzyme Nomenclature | 2.6.1.106 |
IUBMB Enzyme Nomenclature | 2.6.1.106 |
IntEnz | 2.6.1.106 |
MEDLINE | Find literature relating to 2.6.1.106 |
MetaCyc | 2.6.1.106 |
Rhea expert-curated reactions | 2.6.1.106 |
UniProtKB/Swiss-Prot |
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