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ENZYME

ENZYME entry: EC 2.6.1.19

Accepted Name
4-aminobutyrate--2-oxoglutarate transaminase
Alternative Name(s)
4-aminobutyrate aminotransferase
beta-alanine--oxoglutarate aminotransferase
GABA transaminase
gamma-amino-N-butyrate transaminase
Reaction catalysed
2-oxoglutarate + 4-aminobutanoate <=> L-glutamate + succinate semialdehyde
Comment(s)
  • Requires pyridoxal 5'-phosphate.
  • Some preparations also act on beta-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate. cf. EC 2.6.1.120.
Cross-references
BRENDA2.6.1.19
EC2PDB2.6.1.19
ExplorEnz2.6.1.19
PRIAM enzyme-specific profiles2.6.1.19
KEGG Ligand Database for Enzyme Nomenclature2.6.1.19
IUBMB Enzyme Nomenclature2.6.1.19
IntEnz2.6.1.19
MEDLINEFind literature relating to 2.6.1.19
MetaCyc2.6.1.19
Rhea expert-curated reactions2.6.1.19
UniProtKB/Swiss-Prot
P14010, GABAT_EMENIQ6CJ86, GABAT_KLULAO13837, GABAT_SCHPO
P49604, GABAT_USTMAP17649, GABAT_YEASTP94427, GABT_BACSU
Q9BGI0, GABT_BOVINQ21217, GABT_CAEELQ55FI1, GABT_DICDI
P22256, GABT_ECOLIP80404, GABT_HUMANP61922, GABT_MOUSE
P63505, GABT_MYCBOP40829, GABT_MYCLEP9WQ78, GABT_MYCTO
P9WQ79, GABT_MYCTUP80147, GABT_PIGP50554, GABT_RAT
P50457, PUUE_ECOLI

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
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