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ENZYME entry: EC 2.6.1.26

Accepted Name
Thyroid-hormone transaminase.
Alternative Name(s)
3,5-dinitrotyrosine aminotransferase.
Thyroid-hormone aminotransferase.
Reaction catalysed
L-3,5,3'-triiodothyronine + 2-oxoglutarate <=> 3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-2-oxopropanoate + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • Acts on monoiodotyrosine, diiodotyrosine, triiodothyronine, thyroxine and dinitrotyrosine (unlike EC 2.6.1.24, which does not act on dinitrotyrosine).
  • Pyruvate or oxaloacetate can act as acceptor.
Cross-references
BRENDA2.6.1.26
EC2PDB2.6.1.26
ExplorEnz2.6.1.26
PRIAM enzyme-specific profiles2.6.1.26
KEGG Ligand Database for Enzyme Nomenclature2.6.1.26
IUBMB Enzyme Nomenclature2.6.1.26
IntEnz2.6.1.26
MEDLINEFind literature relating to 2.6.1.26
MetaCyc2.6.1.26
Rhea expert-curated reactions2.6.1.26

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-