ENZYME

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.6.1.26

Accepted Name
Thyroid-hormone transaminase.
Alternative Name(s)
3,5-dinitrotyrosine aminotransferase.
Thyroid-hormone aminotransferase.
Reaction catalysed
L-3,5,3'-triiodothyronine + 2-oxoglutarate <=> 3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-2-oxopropanoate + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
Acts on monoiodotyrosine, diiodotyrosine, triiodothyronine, thyroxine and dinitrotyrosine (unlike EC 2.6.1.24, which does not act on dinitrotyrosine). Pyruvate or oxaloacetate can act as acceptor.
Cross-references
BRENDA	2.6.1.26
EC2PDB	2.6.1.26
ExplorEnz	2.6.1.26
PRIAM enzyme-specific profiles	2.6.1.26
KEGG Ligand Database for Enzyme Nomenclature	2.6.1.26
IUBMB Enzyme Nomenclature	2.6.1.26
IntEnz	2.6.1.26
MEDLINE	Find literature relating to 2.6.1.26
MetaCyc	2.6.1.26

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