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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.6.1.26

Accepted Name
Thyroid-hormone transaminase.
Alternative Name(s)
3,5-dinitrotyrosine aminotransferase.
Thyroid-hormone aminotransferase.
Reaction catalysed
L-3,5,3'-triiodothyronine + 2-oxoglutarate <=> 3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-2-oxopropanoate + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • Acts on monoiodotyrosine, diiodotyrosine, triiodothyronine, thyroxine and dinitrotyrosine (unlike EC 2.6.1.24, which does not act on dinitrotyrosine).
  • Pyruvate or oxaloacetate can act as acceptor.
Cross-references
BRENDA2.6.1.26
EC2PDB2.6.1.26
ExplorEnz2.6.1.26
PRIAM enzyme-specific profiles2.6.1.26
KEGG Ligand Database for Enzyme Nomenclature2.6.1.26
IUBMB Enzyme Nomenclature2.6.1.26
IntEnz2.6.1.26
MEDLINEFind literature relating to 2.6.1.26
MetaCyc2.6.1.26

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-