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ENZYME

ENZYME entry: EC 2.6.1.63

PURL: https://purl.expasy.org/enzyme/EC/2.6.1.63
Accepted Name
kynurenine--glyoxylate transaminase
Alternative Name(s)
kynurenine--glyoxylate aminotransferase
Reaction catalysed
  • L-kynurenine + glyoxylate = kynurenate + glycine + H2O
  • 3-hydroxy-L-kynurenine + glyoxylate = xanthurenate + glycine + H2O
Comment(s)
  • This enzyme, characterized from animals, belongs to a family of aminotransferases some members of which can use other amino acceptors (cf. EC 2.6.1.7).
  • The products, 4-(2-aminophenyl)-2,4-dioxobutanoate and 4-(2-amino-3- hydroxyphenyl)-2,4-dioxobutanoate, are converted to kynurenate and xanthurenate, respectively, by spontaneous reactions.
Cross-references
BRENDA2.6.1.63
EC2PDB2.6.1.63
ExplorEnz2.6.1.63
KEGG Ligand Database for Enzyme Nomenclature2.6.1.63
IUBMB Enzyme Nomenclature2.6.1.63
MEDLINEFind literature relating to 2.6.1.63
MetaCyc2.6.1.63
Rhea expert-curated reactions2.6.1.63
UniProtKB/Swiss-Prot
Q5E9N4, AADAT_BOVINQ8N5Z0, AADAT_HUMANQ9WVM8, AADAT_MOUSE
Q64602, AADAT_RATQ0IG34, HKT_AEDAEQ7PRG3, HKT_ANOGA
Q0P5G4, KAT3_BOVINQ7T3E5, KAT3_DANREQ6YP21, KAT3_HUMAN
Q71RI9, KAT3_MOUSEQ58FK9, KAT3_RATQ17CS8, KAT_AEDAE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-