ENZYME entry: EC 2.6.1.63
Accepted Name |
kynurenine--glyoxylate transaminase.
|
Alternative Name(s) |
kynurenine--glyoxylate aminotransferase. |
Reaction catalysed |
- glyoxylate + L-kynurenine <=> glycine + H2O + kynurenate
- 3-hydroxy-L-kynurenine + glyoxylate <=> glycine + H2O + xanthurenate
|
Comment(s) |
- This enzyme, characterized from animals, belongs to a family of
aminotransferases some members of which can use other amino acceptors
(cf. EC 2.6.1.7).
- The products, 4-(2-aminophenyl)-2,4-dioxobutanoate and 4-(2-amino-3-
hydroxyphenyl)-2,4-dioxobutanoate, are converted to kynurenate and
xanthurenate, respectively, by spontaneous reactions.
|
Cross-references |
BRENDA | 2.6.1.63 |
EC2PDB | 2.6.1.63 |
ExplorEnz | 2.6.1.63 |
PRIAM enzyme-specific profiles | 2.6.1.63 |
KEGG Ligand Database for Enzyme Nomenclature | 2.6.1.63 |
IUBMB Enzyme Nomenclature | 2.6.1.63 |
IntEnz | 2.6.1.63 |
MEDLINE | Find literature relating to 2.6.1.63 |
MetaCyc | 2.6.1.63 |
Rhea expert-curated reactions | 2.6.1.63 |
UniProtKB/Swiss-Prot |
Q5E9N4, AADAT_BOVIN; | Q8N5Z0, AADAT_HUMAN; | Q9WVM8, AADAT_MOUSE; |
Q64602, AADAT_RAT; | Q0IG34, HKT_AEDAE; | Q7PRG3, HKT_ANOGA; |
Q0P5G4, KAT3_BOVIN; | Q7T3E5, KAT3_DANRE; | Q6YP21, KAT3_HUMAN; |
Q71RI9, KAT3_MOUSE; | Q58FK9, KAT3_RAT; | Q17CS8, KAT_AEDAE; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
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