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ENZYME entry: EC 2.6.1.63

Accepted Name
Kynurenine--glyoxylate transaminase.
Alternative Name(s)
Kynurenine--glyoxylate aminotransferase.
Reaction catalysed
  • L-kynurenine + glyoxylate <=> kynurenate + glycine + H(2)O
  • 3-hydroxy-L-kynurenine + glyoxylate <=> xanthurenate + glycine + H(2)O
Comment(s)
  • This enzyme, characterized from animals, belongs to a family of aminotransferases some members of which can use other amino acceptors (cf. EC 2.6.1.7).
  • The products, 4-(2-aminophenyl)-2,4-dioxobutanoate and 4-(2-amino-3- hydroxyphenyl)-2,4-dioxobutanoate, are converted to kynurenate and xanthurenate, respectively, by spontaneous reactions.
Cross-references
BRENDA2.6.1.63
EC2PDB2.6.1.63
ExplorEnz2.6.1.63
PRIAM enzyme-specific profiles2.6.1.63
KEGG Ligand Database for Enzyme Nomenclature2.6.1.63
IUBMB Enzyme Nomenclature2.6.1.63
IntEnz2.6.1.63
MEDLINEFind literature relating to 2.6.1.63
MetaCyc2.6.1.63
Rhea expert-curated reactions2.6.1.63
UniProtKB/Swiss-Prot
Q0IG34, HKT_AEDAE;  Q7PRG3, HKT_ANOGA;  Q0P5G4, KAT3_BOVIN;  
Q7T3E5, KAT3_DANRE;  Q6YP21, KAT3_HUMAN;  Q71RI9, KAT3_MOUSE;  
Q58FK9, KAT3_RAT;  Q17CS8, KAT_AEDAE;  

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