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ENZYME entry: EC 2.6.1.76

Accepted Name
Diaminobutyrate--2-oxoglutarate transaminase.
Alternative Name(s)
2,4-diaminobutyrate 4-aminotransferase.
DAB aminotransferase.
DABA aminotransferase.
Diaminibutyric acid aminotransferase.
Diaminobutyrate transaminase.
Diaminobutyrate--2-oxoglutarate aminotransferase.
Reaction catalysed
L-2,4-diaminobutanoate + 2-oxoglutarate <=> L-aspartate 4-semialdehyde + L-glutamate
Cofactor(s)
K(+); Pyridoxal 5'-phosphate.
Comment(s)
  • Differs from EC 2.6.1.46, which has pyruvate as the amino-group acceptor.
  • This is the first enzyme in the ectoine biosynthesis pathway, the other enzymes involved being EC 2.3.1.178 and EC 4.2.1.108.
Cross-references
PROSITEPDOC00519
BRENDA2.6.1.76
EC2PDB2.6.1.76
ExplorEnz2.6.1.76
PRIAM enzyme-specific profiles2.6.1.76
KEGG Ligand Database for Enzyme Nomenclature2.6.1.76
IUBMB Enzyme Nomenclature2.6.1.76
IntEnz2.6.1.76
MEDLINEFind literature relating to 2.6.1.76
MetaCyc2.6.1.76
Rhea expert-curated reactions2.6.1.76
UniProtKB/Swiss-Prot
P56744, DAT_ACIBA;  P44951, DAT_HAEIN;  E1V7V7, DOED_HALED;  
Q9KED4, ECTB_BACHD;  Q5WL78, ECTB_BACSK;  Q7WHI8, ECTB_BORBR;  
Q7W979, ECTB_BORPA;  Q9ZEU7, ECTB_CHRSD;  O52250, ECTB_HALED;  
O06060, ECTB_MARHA;  Q5YW77, ECTB_NOCFA;  Q8ESU8, ECTB_OCEIH;  
Q9AP34, ECTB_SPOPA;  Q6QUY9, ECTB_STRAQ;  Q829L4, ECTB_STRAW;  
Q93RW1, ECTB_STRCO;  Q9KLC2, ECTB_VIBCH;  Q87NZ7, ECTB_VIBPA;  
Q6PR32, ECTB_VIRPA;  Q7M9K2, ECTB_WOLSU;  Q9Z3R2, RHBA_RHIME;  

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