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ENZYME

ENZYME entry: EC 2.6.1.77

Accepted Name
taurine--pyruvate aminotransferase
Reaction catalysed
pyruvate + taurine <=> L-alanine + sulfoacetaldehyde
Comment(s)
  • The enzyme from Bilophila wadsworthia catalyzes a reversible reaction that starts an anaerobic taurine degradation pathway.
  • beta-alanine is also a significant amino group donor.
  • The enzyme from the bacterium Pseudomonas denitrificans PD1222 can also use hypotaurine, producing 2-sulfinoacetaldehyde, which spontaneously hydrolyzes to sulfite and acetaldehyde.
  • Unlike EC 2.6.1.55, 2-oxoglutarate cannot serve as an acceptor for the amino group.
Cross-references
BRENDA2.6.1.77
EC2PDB2.6.1.77
ExplorEnz2.6.1.77
PRIAM enzyme-specific profiles2.6.1.77
KEGG Ligand Database for Enzyme Nomenclature2.6.1.77
IUBMB Enzyme Nomenclature2.6.1.77
IntEnz2.6.1.77
MEDLINEFind literature relating to 2.6.1.77
MetaCyc2.6.1.77
Rhea expert-curated reactions2.6.1.77
UniProtKB/Swiss-Prot
A1B9Z3, HTPA_PARDPE5Y945, TPA_BILW3Q9APM5, TPA_BILWA
D5AKY0, TPA_RHOCB

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
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