ENZYME entry: EC 2.6.1.83

Accepted Name

LL-diaminopimelate aminotransferase

Alternative Name(s)

LL-DAP aminotransferase

LL-DAP-AT

LL-diaminopimelate transaminase

Reaction catalysed

(2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate <=> (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O + L-glutamate

Comment(s)

In vivo, the reaction occurs in the opposite direction to that shown above.
This is one of the final steps in the lysine biosynthesis pathway of plants (ranging from mosses to flowering plants).
Meso-diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate, and the structurally related compounds lysine and ornithine are not substrates.
2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.
It is not yet known if the substrate of the biosynthetic reaction is the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate.

Cross-references

BRENDA

2.6.1.83

EC2PDB

2.6.1.83

ExplorEnz

2.6.1.83

PRIAM enzyme-specific profiles

2.6.1.83

KEGG Ligand Database for Enzyme Nomenclature

2.6.1.83

IUBMB Enzyme Nomenclature

2.6.1.83

IntEnz

2.6.1.83

MEDLINE

Find literature relating to 2.6.1.83

MetaCyc

2.6.1.83

Rhea expert-curated reactions

2.6.1.83

UniProtKB/Swiss-Prot

B0CDH5, DAPAT_ACAM1	A3DK17, DAPAT_ACET2	C4ZG66, DAPAT_AGARV
O66630, DAPAT_AQUAE	Q93ZN9, DAPAT_ARATH	B6YRL2, DAPAT_AZOPC
Q5LC03, DAPAT_BACFN	Q64SY6, DAPAT_BACFR	Q8AAB8, DAPAT_BACTN
Q3AC10, DAPAT_CARHZ	Q5L6M0, DAPAT_CHLAB	Q824A4, DAPAT_CHLCV
Q253K9, DAPAT_CHLFF	Q9PK04, DAPAT_CHLMU	Q9Z856, DAPAT_CHLPN
B0B7W0, DAPAT_CHLT2	Q3KLW3, DAPAT_CHLTA	B0BC25, DAPAT_CHLTB
O84395, DAPAT_CHLTR	B5EGX2, DAPAT_CITBB	B1WSG7, DAPAT_CROS5
B8HJY4, DAPAT_CYAP4	Q3Z8H5, DAPAT_DEHM1	A5FRC5, DAPAT_DEHMB
Q3ZXC8, DAPAT_DEHMC	C0QFJ4, DAPAT_DESAH	B1I544, DAPAT_DESAP
B8IZX8, DAPAT_DESDA	Q18T09, DAPAT_DESHD	Q24S01, DAPAT_DESHY
A8ZXV5, DAPAT_DESOH	Q6AL81, DAPAT_DESPS	Q72BI1, DAPAT_DESVH
B8DJJ6, DAPAT_DESVM	A1VDD3, DAPAT_DESVV	B9M384, DAPAT_GEODF
Q39Z65, DAPAT_GEOMG	Q74GT3, DAPAT_GEOSL	C6E9Q7, DAPAT_GEOSM
A5GD93, DAPAT_GEOUR	B7KL61, DAPAT_GLOC7	Q7NDX4, DAPAT_GLOVI
B8CX89, DAPAT_HALOH	B0TA38, DAPAT_HELMI	C4Z4Y1, DAPAT_LACE2
A9KJ19, DAPAT_LACP7	Q1MR87, DAPAT_LAWIP	B0SEH8, DAPAT_LEPBA
Q04UL5, DAPAT_LEPBJ	Q04YV8, DAPAT_LEPBL	B0SMK7, DAPAT_LEPBP
Q72NJ3, DAPAT_LEPIC	Q8F814, DAPAT_LEPIN	C6BUK3, DAPAT_MARSD
Q58786, DAPAT_METJA	Q6LX26, DAPAT_METMP	A5UN82, DAPAT_METS3
Q2NFU1, DAPAT_METST	O26158, DAPAT_METTH	B0JUM0, DAPAT_MICAN
Q2RK33, DAPAT_MOOTA	B2A250, DAPAT_NATTJ	B2J2U3, DAPAT_NOSP7
Q30ZX9, DAPAT_OLEA2	Q10MQ2, DAPAT_ORYSJ	A6L8U2, DAPAT_PARD8
Q7U4C3, DAPAT_PARMW	Q6MDE0, DAPAT_PARUW	A1ATI6, DAPAT_PELPD
A6L7E4, DAPAT_PHOV8	B1XKF6, DAPAT_PICP2	A3PEY9, DAPAT_PROM0
A2C4T7, DAPAT_PROM1	A2CC97, DAPAT_PROM3	A9BCJ1, DAPAT_PROM4
A2BYM6, DAPAT_PROM5	Q318P3, DAPAT_PROM9	Q7VA14, DAPAT_PROMA
Q7V4Z3, DAPAT_PROMM	Q7UZZ3, DAPAT_PROMP	A2BT75, DAPAT_PROMS
Q46IX2, DAPAT_PROMT	B7JVL5, DAPAT_RIPO1	Q3A1U5, DAPAT_SYNC1
Q31PY6, DAPAT_SYNE7	A0LEA5, DAPAT_SYNFM	Q2JS04, DAPAT_SYNJA
Q2JLL9, DAPAT_SYNJB	Q5N492, DAPAT_SYNP6	A5GIN1, DAPAT_SYNPW
A5GW23, DAPAT_SYNR3	Q0ID68, DAPAT_SYNS3	Q3AW44, DAPAT_SYNS9
Q3AMU5, DAPAT_SYNSC	Q55828, DAPAT_SYNY3	Q8DH57, DAPAT_THEVB
Q10ZC3, DAPAT_TRIEI	B3E933, DAPAT_TRIL1	Q8YM38, DAPT1_NOSS1
Q3MAL4, DAPT1_TRIV2	Q8YP73, DAPT2_NOSS1	Q3MDN5, DAPT2_TRIV2

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.

All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-