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ENZYME

ENZYME entry: EC 2.6.1.83

PURL: https://purl.expasy.org/enzyme/EC/2.6.1.83
Accepted Name
LL-diaminopimelate aminotransferase
Alternative Name(s)
LL-DAP aminotransferase
LL-DAP-AT
LL-diaminopimelate transaminase
Reaction catalysed
(2S,6S)-2,6-diaminopimelate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H2O + H(+)
Comment(s)
  • In vivo, the reaction occurs in the opposite direction to that shown above.
  • This is one of the final steps in the lysine biosynthesis pathway of plants (ranging from mosses to flowering plants).
  • Meso-diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate, and the structurally related compounds lysine and ornithine are not substrates.
  • 2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.
  • It is not yet known if the substrate of the biosynthetic reaction is the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate.
Cross-references
BRENDA2.6.1.83
EC2PDB2.6.1.83
ExplorEnz2.6.1.83
KEGG Ligand Database for Enzyme Nomenclature2.6.1.83
IUBMB Enzyme Nomenclature2.6.1.83
MEDLINEFind literature relating to 2.6.1.83
MetaCyc2.6.1.83
Rhea expert-curated reactions2.6.1.83
UniProtKB/Swiss-Prot
B0CDH5, DAPAT_ACAM1A3DK17, DAPAT_ACET2C4ZG66, DAPAT_AGARV
O66630, DAPAT_AQUAEQ93ZN9, DAPAT_ARATHB6YRL2, DAPAT_AZOPC
Q5LC03, DAPAT_BACFNQ64SY6, DAPAT_BACFRQ8AAB8, DAPAT_BACTN
Q3AC10, DAPAT_CARHZQ5L6M0, DAPAT_CHLABQ824A4, DAPAT_CHLCV
Q253K9, DAPAT_CHLFFQ9PK04, DAPAT_CHLMUQ9Z856, DAPAT_CHLPN
B0B7W0, DAPAT_CHLT2Q3KLW3, DAPAT_CHLTAB0BC25, DAPAT_CHLTB
O84395, DAPAT_CHLTRB5EGX2, DAPAT_CITBBB1WSG7, DAPAT_CROS5
B8HJY4, DAPAT_CYAP4Q3Z8H5, DAPAT_DEHM1A5FRC5, DAPAT_DEHMB
Q3ZXC8, DAPAT_DEHMCC0QFJ4, DAPAT_DESAHB1I544, DAPAT_DESAP
B8IZX8, DAPAT_DESDAQ18T09, DAPAT_DESHDQ24S01, DAPAT_DESHY
A8ZXV5, DAPAT_DESOHQ6AL81, DAPAT_DESPSB9M384, DAPAT_GEODF
Q39Z65, DAPAT_GEOMGQ74GT3, DAPAT_GEOSLC6E9Q7, DAPAT_GEOSM
A5GD93, DAPAT_GEOURB7KL61, DAPAT_GLOC7Q7NDX4, DAPAT_GLOVI
B8CX89, DAPAT_HALOHB0TA38, DAPAT_HELMIC4Z4Y1, DAPAT_LACE2
A9KJ19, DAPAT_LACP7Q1MR87, DAPAT_LAWIPB0SEH8, DAPAT_LEPBA
Q04UL5, DAPAT_LEPBJQ04YV8, DAPAT_LEPBLB0SMK7, DAPAT_LEPBP
Q72NJ3, DAPAT_LEPICQ8F814, DAPAT_LEPINC6BUK3, DAPAT_MARSD
Q58786, DAPAT_METJAQ6LX26, DAPAT_METMPA5UN82, DAPAT_METS3
Q2NFU1, DAPAT_METSTO26158, DAPAT_METTHB0JUM0, DAPAT_MICAN
Q2RK33, DAPAT_MOOTAB2A250, DAPAT_NATTJQ72BI1, DAPAT_NITV2
A1VDD3, DAPAT_NITV4B8DJJ6, DAPAT_NITV9B2J2U3, DAPAT_NOSP7
Q30ZX9, DAPAT_OLEA2Q10MQ2, DAPAT_ORYSJA6L8U2, DAPAT_PARD8
Q7U4C3, DAPAT_PARMWQ6MDE0, DAPAT_PARUWA1ATI6, DAPAT_PELPD
A6L7E4, DAPAT_PHOV8B1XKF6, DAPAT_PICP2A3PEY9, DAPAT_PROM0
A2C4T7, DAPAT_PROM1A2CC97, DAPAT_PROM3A9BCJ1, DAPAT_PROM4
A2BYM6, DAPAT_PROM5Q318P3, DAPAT_PROM9Q7VA14, DAPAT_PROMA
Q7V4Z3, DAPAT_PROMMQ7UZZ3, DAPAT_PROMPA2BT75, DAPAT_PROMS
Q46IX2, DAPAT_PROMTB7JVL5, DAPAT_RIPO1Q3A1U5, DAPAT_SYNC1
Q31PY6, DAPAT_SYNE7A0LEA5, DAPAT_SYNFMQ2JS04, DAPAT_SYNJA
Q2JLL9, DAPAT_SYNJBQ5N492, DAPAT_SYNP6A5GIN1, DAPAT_SYNPW
A5GW23, DAPAT_SYNR3Q0ID68, DAPAT_SYNS3Q3AW44, DAPAT_SYNS9
Q3AMU5, DAPAT_SYNSCQ55828, DAPAT_SYNY3Q8DH57, DAPAT_THEVB
Q10ZC3, DAPAT_TRIEIB3E933, DAPAT_TRIL1Q8YM38, DAPT1_NOSS1
Q3MAL4, DAPT1_TRIV2Q8YP73, DAPT2_NOSS1Q3MDN5, DAPT2_TRIV2

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-