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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Arginine--pyruvate transaminase.
Alternative Name(s)
Arginine:pyruvate transaminase.
Reaction catalysed
L-arginine + pyruvate <=> 5-guanidino-2-oxopentanoate + L-alanine
Pyridoxal 5'-phosphate.
  • While L-arginine is the best substrate, the enzyme exhibits broad substrate specificity, with L-lysine, L-methionine, L-leucine, L-ornithine and L-glutamine also able to act as substrates, but more slowly.
  • Pyruvate cannot be replaced by 2-oxoglutarate as amino-group acceptor.
  • This is the first catalytic enzyme of the arginine transaminase pathway for L-arginine utilization in Pseudomonas aeruginosa.
  • This pathway is only used when the major route of arginine catabolism, i.e. the arginine succinyltransferase pathway, is blocked.
PRIAM enzyme-specific profiles2.6.1.84
KEGG Ligand Database for Enzyme Nomenclature2.6.1.84
IUBMB Enzyme Nomenclature2.6.1.84
MEDLINEFind literature relating to

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-