Home  |  Contact
Due to maintenance work, this service and ftp://ftp.expasy.org will be unavailable from Tuesday August 23rd 18:00 until Wednesday August 24th 08:00 CEST. Apologies for the inconvenience.

ENZYME entry: EC 2.6.1.84

Accepted Name
arginine--pyruvate transaminase.
Alternative Name(s)
arginine:pyruvate transaminase.
Reaction catalysed
L-arginine + pyruvate <=> 5-guanidino-2-oxopentanoate + L-alanine
Comment(s)
  • While L-arginine is the best substrate, the enzyme exhibits broad substrate specificity, with L-lysine, L-methionine, L-leucine, L-ornithine and L-glutamine also able to act as substrates, but more slowly.
  • Pyruvate cannot be replaced by 2-oxoglutarate as amino-group acceptor.
  • This is the first catalytic enzyme of the arginine transaminase pathway for L-arginine utilization in Pseudomonas aeruginosa.
  • This pathway is only used when the major route of arginine catabolism, i.e. the arginine succinyltransferase pathway, is blocked.
Cross-references
BRENDA2.6.1.84
EC2PDB2.6.1.84
ExplorEnz2.6.1.84
PRIAM enzyme-specific profiles2.6.1.84
KEGG Ligand Database for Enzyme Nomenclature2.6.1.84
IUBMB Enzyme Nomenclature2.6.1.84
IntEnz2.6.1.84
MEDLINEFind literature relating to 2.6.1.84
MetaCyc2.6.1.84
Rhea expert-curated reactions2.6.1.84
UniProtKB/Swiss-Prot
Q9HUI9, ARUH_PSEAE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-