ID   2.6.1.86
DE   2-amino-4-deoxychorismate synthase.
AN   2-amino-2-deoxyisochorismate synthase.
AN   ADIC synthase.
CA   (2S)-2-amino-4-deoxychorismate + L-glutamate = chorismate + L-glutamine.
CC   -!- The reaction occurs in the reverse direction to that shown above.
CC   -!- In contrast to most anthranilate-synthase I (ASI) homologs, this
CC       enzyme is not inhibited by tryptophan.
CC   -!- In Streptomyces globisporus, the sequential action of this enzyme and
CC       EC 1.3.99.24, 2-amino-4-deoxychorismate dehydrogenase, leads to the
CC       formation of the benzoxazolinate moiety of the enediyne antitumor
CC       antibiotic C-1027.
CC   -!- In certain Pseudomonads the enzyme participates in the biosynthesis
CC       of phenazine, a precursor for several compounds with antibiotic
CC       activity.
DR   Q8GMH4, SGCD_STRGL ;
//