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ENZYME

ENZYME entry: EC 2.6.1.88

Accepted Name
methionine transaminase
Alternative Name(s)
methionine-oxo-acid transaminase
Reaction catalysed
a 2-oxocarboxylate + L-methionine <=> 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid
Comment(s)
  • The enzyme is most active with L-methionine.
  • It participates in the L-methionine salvage pathway from S-methyl- 5'-thioadenosine, a by-product of polyamine biosynthesis.
  • The enzyme from the bacterium Klebsiella pneumoniae can use several different amino acids as amino donor, with aromatic amino acids being the most effective.
  • The enzyme from the plant Arabidopsis thaliana is also a part of the chain elongation pathway in the biosynthesis of methionine-derived glucosinolates.
Cross-references
BRENDA2.6.1.88
EC2PDB2.6.1.88
ExplorEnz2.6.1.88
PRIAM enzyme-specific profiles2.6.1.88
KEGG Ligand Database for Enzyme Nomenclature2.6.1.88
IUBMB Enzyme Nomenclature2.6.1.88
IntEnz2.6.1.88
MEDLINEFind literature relating to 2.6.1.88
MetaCyc2.6.1.88
Rhea expert-curated reactions2.6.1.88
UniProtKB/Swiss-Prot
Q9M401, BCAT3_ARATHQ9LE06, BCAT4_ARATHQ9C969, ISS1_ARATH
P77806, YBDL_ECOLI

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
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