ENZYME entry: EC 2.6.1.92

Accepted Name

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase

Alternative Name(s)

UDP-4-dehydro-6-deoxy-D-glucose transaminase

UDP-beta-L-threo-pentapyranos-4-ulose transaminase

Reaction catalysed

2-oxoglutarate + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine <=> L-glutamate + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose

Comment(s)

The enzyme transfers the primary amino group of L-glutamate to C-4'' of UDP-4-dehydro sugars, forming a C-N bond in a stereo configuration opposite to that of UDP.
The enzyme from the bacterium Bacillus cereus has been shown to act on UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose, UDP-beta- L-threo-pentapyranos-4-ulose, UDP-4-dehydro-6-deoxy-D-glucose, and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose. cf. EC 2.6.1.34, which catalyzes a similar reaction, but forms the C-N bond in the same stereo configuration as that of UDP.

Cross-references

BRENDA

EC2PDB

ExplorEnz

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature

IUBMB Enzyme Nomenclature

IntEnz

MEDLINE

MetaCyc

Rhea expert-curated reactions

UniProtKB/Swiss-Prot

Q0P8W3, PSEC_CAMJE

Q5QKR7, PSEC_CAMJJ

O25130, PSEC_HELPY

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.

All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-