A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.6.1.92

Accepted Name
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase.
Alternative Name(s)
UDP-4-dehydro-6-deoxy-D-glucose transaminase.
UDP-beta-L-threo-pentapyranos-4-ulose transaminase.
Reaction catalysed
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • The enzyme transfers the primary amino group of L-glutamate to C-4'' of UDP-4-dehydro sugars, forming a C-N bond in a stereo configuration opposite to that of UDP.
  • The enzyme from the bacterium Bacillus cereus has been shown to act on UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose, UDP-beta- L-threo-pentapyranos-4-ulose, UDP-4-dehydro-6-deoxy-D-glucose, and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose.
  • Cf. EC 2.6.1.34, which catalyzes a similar reaction, but forms the C-N bond in the same stereo configuration as that of UDP.
Cross-references
BRENDA2.6.1.92
EC2PDB2.6.1.92
ExplorEnz2.6.1.92
PRIAM enzyme-specific profiles2.6.1.92
KEGG Ligand Database for Enzyme Nomenclature2.6.1.92
IUBMB Enzyme Nomenclature2.6.1.92
IntEnz2.6.1.92
MEDLINEFind literature relating to 2.6.1.92
MetaCyc2.6.1.92
UniProtKB/Swiss-Prot
Q0P8W3, PSEC_CAMJE;  Q5QKR7, PSEC_CAMJJ;  O25130, PSEC_HELPY;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-