A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.6.1.92
| Accepted Name |
|---|
| UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase.
|
| Alternative Name(s) |
|---|
| UDP-4-dehydro-6-deoxy-D-glucose transaminase. |
| UDP-beta-L-threo-pentapyranos-4-ulose transaminase. |
| Reaction catalysed |
|---|
| UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate |
| Cofactor(s) |
|---|
| Pyridoxal 5'-phosphate.
|
| Comment(s) |
|---|
- The enzyme transfers the primary amino group of L-glutamate to C-4''
of UDP-4-dehydro sugars, forming a C-N bond in a stereo configuration
opposite to that of UDP.
- The enzyme from the bacterium Bacillus cereus has been shown to act
on UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose, UDP-beta-
L-threo-pentapyranos-4-ulose, UDP-4-dehydro-6-deoxy-D-glucose,
and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose.
- Cf. EC 2.6.1.34, which catalyzes a similar reaction, but forms the
C-N bond in the same stereo configuration as that of UDP.
|
| Cross-references |
|---|
| BRENDA | 2.6.1.92 |
| EC2PDB | 2.6.1.92 |
| ExplorEnz | 2.6.1.92 |
| PRIAM enzyme-specific profiles | 2.6.1.92 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.6.1.92 |
| IUBMB Enzyme Nomenclature | 2.6.1.92 |
| IntEnz | 2.6.1.92 |
| MEDLINE | Find literature relating to 2.6.1.92 |
| MetaCyc | 2.6.1.92 |
| UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
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