ID   2.6.1.93
DE   neamine transaminase.
AN   glutamate--6'-dehydroparomamine aminotransferase.
CA   2-oxoglutarate + neamine = 6'-oxoparomamine + L-glutamate.
CC   -!- The reaction occurs in vivo in the opposite direction.
CC   -!- Involved in the biosynthetic pathways of several clinically important
CC       aminocyclitol antibiotics, including kanamycin B, butirosin, neomycin
CC       and ribostamycin.
CC   -!- Works in combination with EC 1.1.3.43 to replace the 6'-hydroxy group
CC       of paromamine with an amino group.
CC   -!- The enzyme from the bacterium Streptomyces kanamyceticus can also
CC       catalyze EC 2.6.1.94, which leads to production of kanamycin A.
CC   -!- The enzyme from the bacterium Streptomyces fradiae can also catalyze
CC       EC 2.6.1.95, leading to production of neomycin C.
DR   Q4H4F5, BTRB_NIACI ;  Q6L741, KACL_STRKN ;  Q53U08, NEON_STRFR ;
//