ID 2.6.1.95 DE neomycin C transaminase. CA 2-oxoglutarate + neomycin C = 6'''-deamino-6'''-oxoneomycin C + CA L-glutamate. CC -!- The reaction occurs in vivo in the opposite direction. CC -!- Involved in the biosynthetic pathway of aminoglycoside antibiotics of CC the neomycin family. CC -!- Works in combination with EC 1.1.3.44 to replace the 6'''-hydroxy CC group of 6'''-deamino-6'''-hydroxyneomycin C with an amino group. CC -!- The enzyme, characterized from the bacterium Streptomyces fradiae, CC can also catalyze EC 2.6.1.93. DR Q53U08, NEON_STRFR ; //