A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.6.1.97

Accepted Name
Archaeosine synthase.
Reaction catalysed
L-glutamine + 7-cyano-7-carbaguanine(15) in tRNA + H(2)O <=> L-glutamate + archaeine(15) in tRNA
Comment(s)
In Euryarchaeota the reaction is catalyzed by ArcS. In Crenarchaeota, which do not have an ArcS homolog, the reaction is catalyzed either by a homolog of EC 6.3.4.20 that includes a glutaminase domain (cf. EC 3.5.1.2), or by a homolog of EC 1.7.1.13. The enzyme from the Euryarchaeon Methanocaldococcus jannaschii can also use arginine and ammonium as amino donors.
Cross-references
BRENDA	2.6.1.97
EC2PDB	2.6.1.97
ExplorEnz	2.6.1.97
PRIAM enzyme-specific profiles	2.6.1.97
KEGG Ligand Database for Enzyme Nomenclature	2.6.1.97
IUBMB Enzyme Nomenclature	2.6.1.97
IntEnz	2.6.1.97
MEDLINE	Find literature relating to 2.6.1.97
MetaCyc	2.6.1.97
UniProtKB/Swiss-Prot	D4GTN6, ARCS_HALVD;   Q58428, ARCS_METJA;

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-