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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.6.99.1

Accepted Name
dATP(dGTP)--DNA purinetransferase.
Reaction catalysed
  • dATP + depurinated DNA <=> deoxyribose triphosphate + DNA
  • dGTP + depurinated DNA <=> deoxyribose triphosphate + DNA
Comment(s)
  • The purine residue is transferred on to the apurinic site forming a normal glycosylic bond.
  • dATP reacts at sites of the double-stranded depurinated DNA that lack adenine, and dGTP at sites that lack guanine.
Cross-references
BRENDA2.6.99.1
EC2PDB2.6.99.1
ExplorEnz2.6.99.1
PRIAM enzyme-specific profiles2.6.99.1
KEGG Ligand Database for Enzyme Nomenclature2.6.99.1
IUBMB Enzyme Nomenclature2.6.99.1
IntEnz2.6.99.1
MEDLINEFind literature relating to 2.6.99.1
MetaCyc2.6.99.1

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-