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ENZYME entry: EC 2.7.1.119

Accepted Name
hygromycin-B 7''-O-kinase.
Alternative Name(s)
APH(7'').
hygromycin-B kinase.
hygromycin B phosphotransferase.
Reaction catalysed
ATP + hygromycin B <=> 7''-O-phosphohygromycin B + ADP + H(+)
Comment(s)
Phosphorylates the antibiotics hygromycin B, 1-N-hygromycin B and destomycin, but not hygromycin B2, at the 7''-hydroxy group in the destomic acid ring.
Cross-references
BRENDA2.7.1.119
EC2PDB2.7.1.119
ExplorEnz2.7.1.119
PRIAM enzyme-specific profiles2.7.1.119
KEGG Ligand Database for Enzyme Nomenclature2.7.1.119
IUBMB Enzyme Nomenclature2.7.1.119
IntEnz2.7.1.119
MEDLINEFind literature relating to 2.7.1.119
MetaCyc2.7.1.119
Rhea expert-curated reactions2.7.1.119
UniProtKB/Swiss-Prot
P09979, KHYB_STRHY

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