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ENZYME entry: EC 2.7.1.127

Accepted Name
Inositol-trisphosphate 3-kinase.
Alternative Name(s)
1D-myo-inositol-trisphosphate 3-kinase.
Inositol 1,4,5-trisphosphate 3-kinase.
Ins(1,4,5)P(3) 3-kinase.
IP3 3-kinase.
IP3K.
Reaction catalysed
ATP + 1D-myo-inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
Cofactor(s)
Ca(2+).
Cross-references
BRENDA2.7.1.127
EC2PDB2.7.1.127
ExplorEnz2.7.1.127
PRIAM enzyme-specific profiles2.7.1.127
KEGG Ligand Database for Enzyme Nomenclature2.7.1.127
IUBMB Enzyme Nomenclature2.7.1.127
IntEnz2.7.1.127
MEDLINEFind literature relating to 2.7.1.127
MetaCyc2.7.1.127
Rhea expert-curated reactions2.7.1.127
UniProtKB/Swiss-Prot
P23677, IP3KA_HUMAN;  Q8R071, IP3KA_MOUSE;  P17105, IP3KA_RAT;  
P27987, IP3KB_HUMAN;  P42335, IP3KB_RAT;  Q96DU7, IP3KC_HUMAN;  
Q7TS72, IP3KC_MOUSE;  Q80ZG2, IP3KC_RAT;  Q95Q62, IP3KH_CAEEL;  
Q9US14, IPMK_SCHPO;  P07250, IPMK_YEAST;  

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