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ENZYME entry: EC 2.7.1.137

Accepted Name
phosphatidylinositol 3-kinase.
Alternative Name(s)
1-phosphatidylinositol 3-kinase.
PI3-kinase.
PtdIns-3-kinase.
type III phosphoinositide 3-kinase.
type I phosphatidylinositol kinase.
Reaction catalysed
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+)
Cross-references
BRENDA2.7.1.137
EC2PDB2.7.1.137
ExplorEnz2.7.1.137
PRIAM enzyme-specific profiles2.7.1.137
KEGG Ligand Database for Enzyme Nomenclature2.7.1.137
IUBMB Enzyme Nomenclature2.7.1.137
IntEnz2.7.1.137
MEDLINEFind literature relating to 2.7.1.137
MetaCyc2.7.1.137
Rhea expert-curated reactions2.7.1.137
UniProtKB/Swiss-Prot
P0C5E7, AGE1_CAEBR;  Q94125, AGE1_CAEEL;  O00443, P3C2A_HUMAN;  
Q61194, P3C2A_MOUSE;  Q5RAY1, P3C2A_PONAB;  O00750, P3C2B_HUMAN;  
O75747, P3C2G_HUMAN;  O70167, P3C2G_MOUSE;  O70173, P3C2G_RAT;  
P54673, PI3K1_DICDI;  P42347, PI3K1_SOYBN;  P54674, PI3K2_DICDI;  
P42348, PI3K2_SOYBN;  P54675, PI3K3_DICDI;  P54676, PI3K4_DICDI;  
P42339, PI3K_ARATH;  G5EDY0, PIKI1_CAEEL;  Q9TXI7, PK3C3_CAEEL;  
Q8NEB9, PK3C3_HUMAN;  Q6PF93, PK3C3_MOUSE;  Q5D891, PK3C3_PIG;  
O88763, PK3C3_RAT;  Q6AZN6, PK3C3_XENLA;  P32871, PK3CA_BOVIN;  
P42336, PK3CA_HUMAN;  P42337, PK3CA_MOUSE;  A0A0G2K344, PK3CA_RAT;  
O00329, PK3CD_HUMAN;  O35904, PK3CD_MOUSE;  P48736, PK3CG_HUMAN;  
Q9JHG7, PK3CG_MOUSE;  O02697, PK3CG_PIG;  Q92213, VPS34_CANAX;  
Q8SR56, VPS34_ENCCU;  P50520, VPS34_SCHPO;  P22543, VPS34_YEAST;  

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