ENZYME entry: EC 2.7.1.147
| Accepted Name |
|---|
| ADP-specific glucokinase.
|
| Alternative Name(s) |
|---|
| ADP-dependent glucokinase. |
| Reaction catalysed |
|---|
| ADP + D-glucose <=> AMP + D-glucose 6-phosphate |
| Cofactor(s) |
|---|
| Mg(2+).
|
| Comment(s) |
|---|
- The enzyme from Pyrococcus furiosus is highly specific for D-glucose;
there is some activity with 2-deoxy-D-glucose, but no activity with
D-fructose, D-mannose or D-galactose as the substrate.
- No activity is detected when ADP is replaced by ATP, GDP,
phosphoenolpyruvate, diphosphate or polyphosphate.
|
| Cross-references |
|---|
| BRENDA | 2.7.1.147 |
| EC2PDB | 2.7.1.147 |
| ExplorEnz | 2.7.1.147 |
| PRIAM enzyme-specific profiles | 2.7.1.147 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.147 |
| IUBMB Enzyme Nomenclature | 2.7.1.147 |
| IntEnz | 2.7.1.147 |
| MEDLINE | Find literature relating to 2.7.1.147 |
| MetaCyc | 2.7.1.147 |
| UniProtKB/Swiss-Prot |
| A2VE47, ADPGK_BOVIN; | Q86S40, ADPGK_CAEEL; | Q9BRR6, ADPGK_HUMAN; |
| Q8VDL4, ADPGK_MOUSE; | Q9UYQ3, GLKA_PYRAB; | Q9V2Z6, GLKA_PYRFU; |
| O58328, GLKA_PYRHO; | Q5JE39, GLKA_THEKO; | Q7M537, GLKA_THELN; |
| C6A124, GLKA_THESM; | Q58999, K6PF_METJA; |
|
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