ID   2.7.1.151
DE   inositol-polyphosphate multikinase.
AN   inositol polyphosphate 6-/3-/5-kinase.
AN   IP3/IP4 6-/3-kinase.
AN   IP3/IP4 dual-specificity 6-/3-kinase.
AN   IpK2.
CA   1D-myo-inositol 1,4,5-trisphosphate + 2 ATP = 1D-myo-inositol 1,3,4,5,6-
CA   pentakisphosphate + 2 ADP + 2 H(+).
CC   -!- This enzyme also phosphorylates Ins(1,4,5)P3 to Ins(1,3,4,5)P4,
CC       Ins(1,3,4,5)P4 to Ins(1,3,4,5,6)P5, and Ins(1,3,4,5,6)P4 to
CC       Ins(PP)P4, isomer unknown.
CC   -!- The enzyme from the plant Arabidopsis thaliana can also phosphorylate
CC       Ins(1,3,4,6)P4 and Ins(1,2,3,4,6)P5 at the D-5-position to produce
CC       1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate (InsP6),
CC       respectively.
CC   -!- Yeast produces InsP6 from Ins(1,4,5)P3 by the actions of this enzyme
CC       and EC 2.7.1.158.
DR   A2X5H5, IPK2_ORYSI ;  Q6H545, IPK2_ORYSJ ;  Q9LY23, IPMKA_ARATH;
DR   Q9FLT2, IPMKB_ARATH;  Q8NFU5, IPMK_HUMAN ;  Q7TT16, IPMK_MOUSE ;
DR   Q99NI4, IPMK_RAT   ;  Q9US14, IPMK_SCHPO ;  P07250, IPMK_YEAST ;
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